Literature DB >> 1820795

[Experimental anti-arrhythmic effects of zhigancao (prepared licorice) injection].

R Chen1, C Yuan.   

Abstract

Zhigancao injection can antagonise the arrhythmia induced by chloroform, adrenaline, aconitine, strophanthine K and barium chloride, slow the heart rate, prolong P-R and Q-T intervals and antagonise the positive chronotropic response induced by isoprenaline. The LD50 of zhigancao injection is 41.2g/kg in nice by intraperitoneal.

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Year:  1991        PMID: 1820795

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  2 in total

1.  Application of the myocardial tissue/silicon substrate microelectrode array technology on detecting the effection of Zhigancao Decoction medicated serum on cardiac electrophysiology.

Authors:  Juan Sun; Yanmei Lu; Huang Yan; Yujun Guo; Ainiwaer Aikemu
Journal:  Int J Clin Exp Med       Date:  2015-02-15

2.  18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels.

Authors:  Yi-mei Du; Cheng-kun Xia; Ning Zhao; Qian Dong; Ming Lei; Jia-hong Xia
Journal:  Acta Pharmacol Sin       Date:  2012-05-21       Impact factor: 6.150

  2 in total

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