Literature DB >> 18205374

Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions.

Antonio Osorio-Lozada1, Horacio F Olivo.   

Abstract

An indene-based thiazolidinethione chiral auxiliary was prepared in two steps from trans-1-amino-2-indanol. Chlorotitanium enolates of this chiral auxiliary delivered excellent diastereoselectivities in propionate and acetate aldol additions. The chiral auxiliary was easily removed to deliver several valuable functionalities.

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Year:  2008        PMID: 18205374     DOI: 10.1021/ol702980p

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Asymmetric Synthesis of Homocitric Acid Lactone.

Authors:  Leslie A Nickerson; Valerie Huynh; Edward I Balmond; Stephen P Cramer; Jared T Shaw
Journal:  J Org Chem       Date:  2016-10-21       Impact factor: 4.354

Review 2.  Synthetic routes and biological evaluation of largazole and its analogues as potent histone deacetylase inhibitors.

Authors:  Shang Li; Hequan Yao; Jinyi Xu; Sheng Jiang
Journal:  Molecules       Date:  2011-06-07       Impact factor: 4.411

  2 in total

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