Literature DB >> 18205246

Insight, quality of life, and functional capacity in middle-aged and older adults with schizophrenia.

Ashley S Roseman1, John Kasckow, Ian Fellows, Katerine Osatuke, Thomas L Patterson, Somaia Mohamed, Sidney Zisook.   

Abstract

OBJECTIVE: The quality of life (QOL) for individuals with schizophrenia is determined by a number of factors, not limited to symptomatology. The current study examined lack of insight as one such factor that may influence subjective QOL or functional capacity. It was hypothesized that insight would significantly interact with symptom severity to influence subjective QOL. Insight was not expected to influence the relation between symptom severity and functional capacity.
METHODS: Participants were middle-aged and older outpatients who met diagnostic criteria for schizophrenia or schizoaffective disorder, and subsyndromal depression. Insight, psychopathology, and subjective QOL were assessed via semi-structured interviews and functional capacity was assessed via performance-based measures.
RESULTS: Insight interacts with negative symptom severity to predict subjective QOL. Severity of negative symptoms and insight contribute directly to functional capacity.
CONCLUSIONS: Individuals with intact insight may be better able to manage their symptoms, resulting in improved QOL. Treatment implications for improving the QOL of middle age and older adults with schizophrenia are discussed.

Entities:  

Mesh:

Year:  2008        PMID: 18205246      PMCID: PMC3428424          DOI: 10.1002/gps.1978

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN: 0885-6230            Impact factor:   3.485


  41 in total

1.  UCSD Performance-Based Skills Assessment: development of a new measure of everyday functioning for severely mentally ill adults.

Authors:  T L Patterson; S Goldman; C L McKibbin; T Hughs; D V Jeste
Journal:  Schizophr Bull       Date:  2001       Impact factor: 9.306

2.  The assessment of insight in psychosis.

Authors:  A David; A Buchanan; A Reed; O Almeida
Journal:  Br J Psychiatry       Date:  1992-11       Impact factor: 9.319

3.  Compliance with neuroleptic medication in outpatients with schizophrenia; relationship to subjective response to neuroleptics; attitudes to medication and insight.

Authors:  J Garavan; S Browne; M Gervin; A Lane; C Larkin; E O'Callaghan
Journal:  Compr Psychiatry       Date:  1998 Jul-Aug       Impact factor: 3.735

4.  Psychopathology and quality of life in schizophrenia.

Authors:  S Packer; J Husted; S Cohen; G Tomlinson
Journal:  J Psychiatry Neurosci       Date:  1997-07       Impact factor: 6.186

5.  Social skills performance assessment among older patients with schizophrenia.

Authors:  T L Patterson; S Moscona; C L McKibbin; K Davidson; D V Jeste
Journal:  Schizophr Res       Date:  2001-03-30       Impact factor: 4.939

6.  Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life.

Authors:  B C Ho; P Nopoulos; M Flaum; S Arndt; N C Andreasen
Journal:  Am J Psychiatry       Date:  1998-09       Impact factor: 18.112

7.  Quality of life in schizophrenia: contributions of anxiety and depression.

Authors:  J D Huppert; K A Weiss; R Lim; S Pratt; T E Smith
Journal:  Schizophr Res       Date:  2001-09-01       Impact factor: 4.939

8.  Characterizing quality of life among patients with chronic mental illness: a critical examination of the self-report methodology.

Authors:  M Atkinson; S Zibin; H Chuang
Journal:  Am J Psychiatry       Date:  1997-01       Impact factor: 18.112

9.  Correlates of subjective and functional outcomes in outpatient clinic attendees with schizophrenia and schizoaffective disorder.

Authors:  Alex Hofer; Maria A Rettenbacher; Christian G Widschwendter; Georg Kemmler; Martina Hummer; W Wolfgang Fleischhacker
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2005-11-29       Impact factor: 5.270

Review 10.  Psychoeducation for schizophrenia.

Authors:  E Pekkala; L Merinder
Journal:  Cochrane Database Syst Rev       Date:  2002
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  8 in total

Review 1.  Elderly patients with schizophrenia and depression: diagnosis and treatment.

Authors:  Kandi Felmet; Sidney Zisook; John W Kasckow
Journal:  Clin Schizophr Relat Psychoses       Date:  2011-01

2.  Insight and Treatment Outcomes in Schizophrenia: Post-hoc Analysis of a Long-term, Double-blind Study Comparing Lurasidone and Quetiapine XR.

Authors:  Philip D Harvey; Cynthia O Siu; Antony D Loebel
Journal:  Innov Clin Neurosci       Date:  2017-12-01

3.  A comprehensive model of predictors of quality of life in older adults with schizophrenia: results from the CSA study.

Authors:  Nicolas Hoertel; Léa Rotenberg; Carlos Blanco; Vincent Camus; Caroline Dubertret; Véronique Charlot; Franck Schürhoff; Pierre Vandel; Frédéric Limosin
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2020-05-15       Impact factor: 4.328

4.  Psychometric properties of the abbreviated version of the Scale to Assess Unawareness in Mental Disorder in schizophrenia.

Authors:  Pierre Michel; Karine Baumstarck; Pascal Auquier; Xavier Amador; Rémy Dumas; Jessica Fernandez; Christophe Lancon; Laurent Boyer
Journal:  BMC Psychiatry       Date:  2013-09-22       Impact factor: 3.630

5.  Recorded poor insight as a predictor of service use outcomes: cohort study of patients with first-episode psychosis in a large mental healthcare database.

Authors:  Neha Ramu; Anna Kolliakou; Jyoti Sanyal; Rashmi Patel; Robert Stewart
Journal:  BMJ Open       Date:  2019-06-12       Impact factor: 2.692

6.  Cognitive insight and quality of life among psychiatric outpatients.

Authors:  Vathsala Sagayadevan; Anitha Jeyagurunathan; Ying Wen Lau; Saleha Shafie; Sherilyn Chang; Hui Lin Ong; Ellaisha Samari; Swapna Kamal Verma; Siow Ann Chong; Mythily Subramaniam
Journal:  BMC Psychiatry       Date:  2019-06-28       Impact factor: 3.630

7.  Relationships between cognitive performance, clinical insight and regional brain volumes in schizophrenia.

Authors:  Erkan Alkan; Simon L H Evans
Journal:  Schizophrenia (Heidelb)       Date:  2022-04-04

Review 8.  Assessing the Relationship between Performance on the University of California Performance Skills Assessment (UPSA) and Outcomes in Schizophrenia: A Systematic Review and Evidence Synthesis.

Authors:  Shelagh Szabo; Elizabeth Merikle; Greta Lozano-Ortega; Lauren Powell; Thomas Macek; Stephanie Cline
Journal:  Schizophr Res Treatment       Date:  2018-12-27
  8 in total

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