Literature DB >> 18201498

Clostridium difficile in urology.

M Hossain1, T J Crook, S R Keoghane.   

Abstract

INTRODUCTION: The objective was to determine the incidence of Clostridium difficile infection in a UK urology ward from 2000 to 2005, and correlate and compare the data with other specialty wards and national figures. PATIENTS AND METHODS: Urology patients with a positive stool culture for C. difficile between 2000 and 2005 were identified from a hospital database. The medical records of these patients were reviewed and data such as antibiotic use, urological diagnosis and elective/emergency status of the patient were recorded and analysed. The number of C. difficile cases on an elderly care ward, an acute medical ward and an acute surgical ward were also recorded for this period. Data on the number of admissions and occupied bed-days on all 4 wards were compared.
RESULTS: There were 33 cases of C. difficile on the urology ward between 2000 and 2005. The incidence of this infection varied between 10.2 and 48.4 cases per 10,000 patient episodes (mean 21.0). There was a significant difference between the number of C. difficile cases per 1000 patient days between the urology ward and the acute medical ward (P = 0.002) and the elderly care ward (P = 0.03).
CONCLUSIONS: There is no evidence to suggest that there has been an increase in the incidence of C. difficile in a UK urology ward. The rates on the urology ward were lower than the national average, and significantly lower than those rates on an acute medical ward and an elderly care ward. There is a 0.21% chance of a patient testing positive for C. difficile during their stay on a urology ward.

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Mesh:

Year:  2008        PMID: 18201498      PMCID: PMC2216714          DOI: 10.1308/003588408X242358

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  21 in total

1.  Screening for carriage and nosocomial acquisition of Clostridium difficile by culture: a study of 284 admissions of elderly patients to six general hospitals in Wales.

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Review 2.  Clinical practice. Antibiotic-associated diarrhea.

Authors:  John G Bartlett
Journal:  N Engl J Med       Date:  2002-01-31       Impact factor: 91.245

Review 3.  Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review.

Authors:  Claudia Thomas; Mark Stevenson; Thomas V Riley
Journal:  J Antimicrob Chemother       Date:  2003-05-13       Impact factor: 5.790

4.  Specific risk factors for Clostridium difficile-associated diarrhea: a prospective, multicenter, case control evaluation.

Authors:  Kimi S Vesta; Paula G Wells; Chris A Gentry; Wanda J Stipek
Journal:  Am J Infect Control       Date:  2005-10       Impact factor: 2.918

5.  Underlying disease severity as a major risk factor for nosocomial Clostridium difficile diarrhea.

Authors:  Lorraine Kyne; Stavros Sougioultzis; Lynne V McFarland; Ciarán P Kelly
Journal:  Infect Control Hosp Epidemiol       Date:  2002-11       Impact factor: 3.254

6.  Antimicrobial agents implicated in Clostridium difficile toxin-associated diarrhea of colitis.

Authors:  J G Bartlett
Journal:  Johns Hopkins Med J       Date:  1981-07

7.  Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia.

Authors:  J G Bartlett; T W Chang; M Gurwith; S L Gorbach; A B Onderdonk
Journal:  N Engl J Med       Date:  1978-03-09       Impact factor: 91.245

8.  Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies.

Authors:  Sandra Dial; Khalid Alrasadi; Chantal Manoukian; Allen Huang; Dick Menzies
Journal:  CMAJ       Date:  2004-07-06       Impact factor: 8.262

9.  Clostridium difficile and the aetiology of pseudomembranous colitis.

Authors:  H E Larson; A B Price; P Honour; S P Borriello
Journal:  Lancet       Date:  1978-05-20       Impact factor: 79.321

10.  Clostridium difficile in a geriatric unit: a prospective epidemiological study employing a novel S-layer typing method.

Authors:  Jodie McCoubrey; John Starr; Heather Martin; Ian R Poxton
Journal:  J Med Microbiol       Date:  2003-07       Impact factor: 2.472

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