Literature DB >> 18200377

[Idiopathic pulmonary hemosiderosis treated with azathioprine in a child].

Clemax Couto Sant'Anna1, Angélica Almada Horta, Mônica Tessinari Rangel Tura, Maria de Fatima Bazhuni Pombo March, Sidnei Ferreira, Rafaela Baroni Aurilio, Débora Brandão Vieira.   

Abstract

Idiopathic pulmonary hemosiderosis (IPH), the main cause of pulmonary hemosiderosis in children, is characterized by intermittent alveolar bleeding and hemosiderin-laden macrophages in sputum and in gastric lavage. The treatment is based on corticosteroids and cytotoxic drugs, under special conditions. We describe the case of a 7-year-old girl with IPH who achieved partial clinical remission with high doses of corticosteroids. However, the treatment had to be discontinued because the patient developed Cushing's syndrome. Treatment was started with an azathioprine-corticosteroid combination and then changed to azathioprine alone, which was maintained for four years, with excellent results.

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Year:  2007        PMID: 18200377     DOI: 10.1590/s1806-37132007000600020

Source DB:  PubMed          Journal:  J Bras Pneumol        ISSN: 1806-3713            Impact factor:   2.624


  2 in total

1.  Idiopathic pulmonary hemosiderosis in a 9-year-old girl.

Authors:  E Kamienska; T Urasinski; A Gawlikowska-Sroka; B Glura; A Pogorzelski
Journal:  Eur J Med Res       Date:  2009-12-07       Impact factor: 2.175

2.  A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis.

Authors:  Chana I C Chin; Shirleen Loloyan Kohn; Thomas G Keens; Monique F Margetis; Roberta M Kato
Journal:  Orphanet J Rare Dis       Date:  2015-08-20       Impact factor: 4.303

  2 in total

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