Literature DB >> 18200371

[Clinical aspects of pulmonary tuberculosis in elderly patients from a university hospital in Rio de Janeiro, Brazil].

João Paulo Cantalice Filho1, Clemax Couto Sant Anna, Márcio Neves Bóia.   

Abstract

OBJECTIVE: To evaluate clinical aspects and the diagnosis of pulmonary tuberculosis (PT) in the aged.
METHODS: We compared 117 patients over 60 years of age (elderly group) and 464 patients aged 15 to 49 years old (nonelderly group) treated at the Thoracic Diseases Institute of the Federal University of Rio de Janeiro, from 1980 to 1996.
RESULTS: Previous history of PT was predominant in the elderly group (OR = 2.09; 95% CI = 1.26-3.45; p = 0.002), whereas household contact with PT was predominant in the nonelderly group (OR = 0.26; 95% CI = 0.10-0.66; p = 0.002). Mean time for diagnosis was 90 days in the elderly group and 60 days in the nonelderly group. In the elderly group, dyspnea (OR = 1.64; 95% CI = 1.06-2.53; p = 0.018) and weight loss (OR = 1.66; 95% CI = 1.01-2.82; p = 0.047) were predominant. In the nonelderly group, hemoptysis (OR = 0.51; 95% CI = 0.32-0.81; p = 0.002), chest pain (OR = 0.62; 95% CI = 0.40-0.97; p = 0.027) and fever (OR = 0.55; 95% CI = 0.35-0.86; p = 0.006) were more common. The most common radiological abnormalities were infiltrates and cavitations. Bilateral involvement was more common in the elderly patients (OR = 1.76; 95% CI = 1.12-2.78; p = 0.009). There were no differences between the two groups regarding positivity for Mycobacterium tuberculosis identified through tuberculin skin testing, sputum smear microscopy and culture.
CONCLUSIONS: There are few clinical and laboratory differences between the age groups. The delayed diagnosis in the elderly group can be explained by the low clinical suspicion in these patients.

Entities:  

Mesh:

Year:  2007        PMID: 18200371     DOI: 10.1590/s1806-37132007000600014

Source DB:  PubMed          Journal:  J Bras Pneumol        ISSN: 1806-3713            Impact factor:   2.624


  4 in total

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Journal:  Cureus       Date:  2020-05-27

2.  Radiological significance of high-resolution computed tomography for elderly pulmonary tuberculosis patients - an analysis with culture test.

Authors:  Niranjan Sahu; Somadatta Das; Rabindra Nath Padhy
Journal:  Pol J Radiol       Date:  2020-03-06

3.  Features of Adolescents Tuberculosis at a Referral TB's Hospital in Tehran, Iran.

Authors:  Ferial Lotfian; Mohammad Reza Bolursaz; Soheila Khalilzadeh; Noshin Baghaie; Maryam Hassanzad; Aliakbar Velayati
Journal:  Mediterr J Hematol Infect Dis       Date:  2016-01-01       Impact factor: 2.576

4.  Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients.

Authors:  Simone de Sousa Elias Nihues; Eliane Viana Mancuzo; Nara Sulmonetti; Flávia Patussi Correia Sacchi; Vanessa de Souza Viana; Eduardo Martins Netto; Silvana Spindola Miranda; Julio Croda
Journal:  Braz J Infect Dis       Date:  2015-08-05       Impact factor: 3.257

  4 in total

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