Literature DB >> 18200018

Erectile dysfunction as a harbinger for increased cardiometabolic risk.

K L Billups1, A J Bank, H Padma-Nathan, S D Katz, R A Williams.   

Abstract

In August 2003, the Minority Health Institute (MHI) convened an Expert Advisory Panel of cardiologists and urologists to design a new practice model algorithm that uses erectile dysfunction (ED) as a clinical tool for early identification of men with systemic vascular disease. The MHI algorithm noted ED as a marker for the presence of cardiovascular disease and suggested that ED may well be a cardiovascular risk equivalent warranting aggressive secondary prevention management strategies, even in the absence of other cardiac or peripheral vascular symptoms. The MHI algorithm stipulates that all men 25 years of age and older should be asked about ED as a routine part of the cardiovascular history during any office visit. The presence of ED should prompt an aggressive assessment for occult vascular disease; many men with erectile difficulty would benefit from early, aggressive management of cardiovascular risk factors with both lifestyle modification and pharmacotherapy to achieve optimal target goals under the existing treatment guidelines. Since publication of the algorithm in 2005, additional research studies have further supported the advisory panel recommendations.

Entities:  

Mesh:

Year:  2008        PMID: 18200018     DOI: 10.1038/sj.ijir.3901634

Source DB:  PubMed          Journal:  Int J Impot Res        ISSN: 0955-9930            Impact factor:   2.896


  18 in total

1.  Hypovitaminosis D is associated with erectile dysfunction in type 2 diabetes.

Authors:  Nicola Caretta; Saula Vigili de Kreutzenberg; Umberto Valente; Gabriella Guarneri; Alberto Ferlin; Angelo Avogaro; Carlo Foresta
Journal:  Endocrine       Date:  2016-01-12       Impact factor: 3.633

2.  Prevalence and risk factors of erectile dysfunction in Niger delta region, Nigeria.

Authors:  A U Idung; F Abasiubong; I A Ukott; S B Udoh; B C Unadike
Journal:  Afr Health Sci       Date:  2012-06       Impact factor: 0.927

3.  Does erectile dysfunction contribute to cardiovascular disease risk prediction beyond the Framingham risk score?

Authors:  Andre B Araujo; Susan A Hall; Peter Ganz; Gretchen R Chiu; Raymond C Rosen; Varant Kupelian; Thomas G Travison; John B McKinlay
Journal:  J Am Coll Cardiol       Date:  2010-01-26       Impact factor: 24.094

4.  Analysis of pomegranate juice components in rat corpora cavernosal relaxation.

Authors:  C V Oztekin; S Gur; N A Abdulkadir; M Kartal; M Karabakan; A O Akdemir; C S Gökkaya; M Cetinkaya
Journal:  Int J Impot Res       Date:  2013-08-01       Impact factor: 2.896

5.  Energy restriction ameliorates metabolic syndrome-induced cavernous tissue structural modifications in aged rats.

Authors:  Inês Tomada; Dalila Fernandes; João Tiago Guimarães; Henrique Almeida; Delminda Neves
Journal:  Age (Dordr)       Date:  2012-09-26

6.  Telmisartan, ramipril and their combination improve endothelial function in different tissues in a murine model of cholesterol-induced atherosclerosis.

Authors:  N Schlimmer; M Kratz; M Böhm; M Baumhäkel
Journal:  Br J Pharmacol       Date:  2011-06       Impact factor: 8.739

7.  Erectile dysfunction and mortality.

Authors:  Andre B Araujo; Thomas G Travison; Peter Ganz; Gretchen R Chiu; Varant Kupelian; Raymond C Rosen; Susan A Hall; John B McKinlay
Journal:  J Sex Med       Date:  2009-06-15       Impact factor: 3.802

8.  Reversal of voltage-dependent erectile responses in the Zucker obese-diabetic rat by rosuvastatin-altered RhoA/Rho-kinase signaling.

Authors:  Christopher J Wingard; Fatiha Moukdar; Raju Y Prasad; Brook L Cathey; Lois Wilkinson
Journal:  J Sex Med       Date:  2009-03       Impact factor: 3.802

9.  Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue.

Authors:  I Tomada; R Negrão; H Almeida; D Neves
Journal:  Age (Dordr)       Date:  2013-10-09

Review 10.  Erectile dysfunction as a cardiovascular risk factor in patients with diabetes.

Authors:  Giorgio Gandaglia; Andrea Salonia; Niccolò Passoni; Piero Montorsi; Alberto Briganti; Francesco Montorsi
Journal:  Endocrine       Date:  2012-09-05       Impact factor: 3.633

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