Literature DB >> 18199862

A citywide protocol for primary PCI in ST-segment elevation myocardial infarction.

Michel R Le May1, Derek Y So, Richard Dionne, Chris A Glover, Michael P V Froeschl, George A Wells, Richard F Davies, Heather L Sherrard, Justin Maloney, Jean-François Marquis, Edward R O'Brien, John Trickett, Pierre Poirier, Sheila C Ryan, Andrew Ha, Phil G Joseph, Marino Labinaz.   

Abstract

BACKGROUND: If primary percutaneous coronary intervention (PCI) is performed promptly, the procedure is superior to fibrinolysis in restoring flow to the infarct-related artery in patients with ST-segment elevation myocardial infarction. The benchmark for a timely PCI intervention has become a door-to-balloon time of less than 90 minutes. Whether regional strategies can be developed to achieve this goal is uncertain.
METHODS: We developed an integrated-metropolitan-area approach in which all patients with ST-segment elevation myocardial infarction were referred to a specialized center for primary PCI. We sought to determine whether there was a difference in door-to-balloon times between patients who were referred directly from the field by paramedics trained in the interpretation of electrocardiograms and patients who were referred by emergency department physicians.
RESULTS: Between May 1, 2005, and April 30, 2006, a total of 344 consecutive patients with ST-segment elevation myocardial infarction were referred for primary PCI: 135 directly from the field and 209 from emergency departments. Primary PCI was performed in 93.6% of patients. The median door-to-balloon time was shorter in patients referred from the field (69 minutes; interquartile range, 43 to 87) than in patients needing interhospital transfer (123 minutes; interquartile range, 101 to 153; P<0.001). Door-to-balloon times of less than 90 minutes were achieved in 79.7% of patients who were transferred from the field and in 11.9% of those transferred from emergency departments (P<0.001).
CONCLUSIONS: Guideline door-to-balloon-times were more often achieved when trained paramedics independently triaged and transported patients directly to a designated primary PCI center than when patients were referred from emergency departments. Copyright 2008 Massachusetts Medical Society.

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Year:  2008        PMID: 18199862     DOI: 10.1056/NEJMoa073102

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  50 in total

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Review 3.  Reperfusion options in ST-elevation myocardial infarction patients with expected delays.

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Authors:  Robert C Welsh; Andrew Travers; Thao Huynh; Warren J Cantor
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Review 6.  Code STEMI: implementation of a city-wide program for rapid assessment and management of myocardial infarction.

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7.  Treatment delay in ST elevation myocardial infarction care in a community hospital -- a cautionary tale.

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8.  Providing optimal regional care for ST-segment elevation myocardial infarction: a prospective cohort study of patients in the Hamilton Niagara Haldimand Brant Local Health Integration Network.

Authors:  Mathew Mercuri; Michelle Welsford; Jon-David Schwalm; Shamir R Mehta; Purnima Rao-Melacini; Tej Sheth; Michael Rokoss; Sanjit S Jolly; James L Velianou; Madhu K Natarajan
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9.  Association between treatment at an ST-segment elevation myocardial infarction center and neurologic recovery after out-of-hospital cardiac arrest.

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10.  Effect of regional cooperative rescue systems based on chest pain centers for patients with acute myocardial infarction in a first-tier city in China.

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