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Literature DB >> 18199414

Tug of war at the exit door.

Abstract

The lipid sphingosine-1-phosphate has been identified as a key exit signal for lymph nodes. In this issue of Immunity, Pham et al. (2008) show that its action can only be understood in the context of retention signals transduced by CCR7.

Entities: Chemical Gene

Mesh：

Substances：

Year: 2008 PMID： 18199414 PMCID： PMC2719829 DOI： 10.1016/j.immuni.2008.01.001

Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745

7 in total

1. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.

Authors: F Sallusto; D Lenig; R Förster; M Lipp; A Lanzavecchia
Journal: Nature Date: 1999-10-14 Impact factor: 49.962

2. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

Authors: Suzanne Mandala; Richard Hajdu; James Bergstrom; Elizabeth Quackenbush; Jenny Xie; James Milligan; Rosemary Thornton; Gan-Ju Shei; Deborah Card; CarolAnn Keohane; Mark Rosenbach; Jeffrey Hale; Christopher L Lynch; Kathleen Rupprecht; William Parsons; Hugh Rosen
Journal: Science Date: 2002-03-28 Impact factor: 47.728

3. In silico models for cellular and molecular immunology: successes, promises and challenges.

Authors: Arup K Chakraborty; Michael L Dustin; Andrey S Shaw
Journal: Nat Immunol Date: 2003-10 Impact factor: 25.606

Review 4. Stop and go traffic to tune T cell responses.

Authors: Michael L Dustin
Journal: Immunity Date: 2004-09 Impact factor: 31.745

5. CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node.

Authors: Takaharu Okada; Jason G Cyster
Journal: J Immunol Date: 2007-03-01 Impact factor: 5.422

6. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses.

Authors: Sindy H Wei; Hugh Rosen; Melanie P Matheu; M Germana Sanna; Sheng-Kai Wang; Euijung Jo; Chi-Huey Wong; Ian Parker; Michael D Cahalan
Journal: Nat Immunol Date: 2005-11-06 Impact factor: 25.606

7. Lymph node topology dictates T cell migration behavior.

Authors: Joost B Beltman; Athanasius F M Marée; Jennifer N Lynch; Mark J Miller; Rob J de Boer
Journal: J Exp Med Date: 2007-03-26 Impact factor: 14.307

7 in total

4 in total

Tug of war at the exit door.

1. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.

2. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

3. In silico models for cellular and molecular immunology: successes, promises and challenges.

Review 4. Stop and go traffic to tune T cell responses.

5. CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node.

6. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses.

7. Lymph node topology dictates T cell migration behavior.

Review 1. Reverse leukocyte migration can be attractive or repulsive.

2. On-lattice simulation of T cell motility, chemotaxis, and trafficking in the lymph node paracortex.

3. Combinatorial guidance by CCR7 ligands for T lymphocytes migration in co-existing chemokine fields.

Review 4. Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation.