| Literature DB >> 18198839 |
Atallah F Ahmed1, Zhi-Hong Wen, Jui-Hsin Su, Ya-Ting Hsieh, Yang-Chang Wu, Wan-Ping Hu, Jyh-Horng Sheu.
Abstract
Chemical investigation of a Formosan soft coral, Sinularia gibberosa, has led to the isolation of eight oxygenated cembranoids, 1- 8, including seven new compounds, gibberosenes A-G ( 2- 8). None of these compounds were found to be cytotoxic toward a limited panel of cancer cell lines. Compound 1 significantly inhibited the accumulation of the pro-inflammatory COX-2 protein of the LPS-stimulated RAW264.7 macrophage cells.Entities:
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Year: 2008 PMID： 18198839 DOI： 10.1021/np070356p
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050