| Literature DB >> 18198489 |
Gi-Wook Hwang1, Tatsuya Hayashi, Kayoko Kita, Tsutomu Takahashi, Shusuke Kuge, Akira Naganuma.
Abstract
We performed functional gene screening, using a siRNA library targeting 8,500 human genes, to identify proteins that are involved in the susceptibility of cells to methylmercury. Screening revealed that downregulation of the gene for phosphatidylinositol glycan class B (PIGB) by siRNA confers resistance to methylmercury in HEK293 cells.Entities:
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Year: 2007 PMID： 18198489 DOI： 10.2131/jts.32.581
Source DB: PubMed Journal: J Toxicol Sci ISSN： 0388-1350 Impact factor: 2.196