Literature DB >> 18197783

Progesterone receptor isoform functions in normal breast development and breast cancer.

Anastasia Kariagina1, Mark D Aupperlee, Sandra Z Haslam.   

Abstract

Progesterone acting through two isoforms of the progesterone receptor (PR), PRA and PRB, regulates proliferation and differentiation in the normal mammary gland in mouse, rat, and human. Progesterone and PR have also been implicated in the etiology and pathogenesis of human breast cancer. The focus of this review is recent advances in understanding the role of the PR isoform-specific functions in the normal breast and in breast cancer. Also discussed is information obtained from rodent studies and their relevance to our understanding of the role of progestins in breast cancer etiology.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18197783      PMCID： PMC2829978          DOI： 10.1615/critreveukargeneexpr.v18.i1.20

Source DB:  PubMed          Journal:  Crit Rev Eukaryot Gene Expr        ISSN： 1045-4403            Impact factor:   1.807


  96 in total

1.  Proliferative and secretory activity in human breast during natural and artificial menstrual cycles.

Authors:  J J Going; T J Anderson; S Battersby; C C MacIntyre
Journal:  Am J Pathol       Date:  1988-01       Impact factor: 4.307

2.  Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements.

Authors:  Sarah C Roemer; Douglas C Donham; Lori Sherman; Vickie H Pon; Dean P Edwards; Mair E A Churchill
Journal:  Mol Endocrinol       Date:  2006-08-24

3.  Detection of progesterone receptor forms A and B by immunohistochemical analysis.

Authors:  P A Mote; J F Johnston; T Manninen; P Tuohimaa; C L Clarke
Journal:  J Clin Pathol       Date:  2001-08       Impact factor: 3.411

Review 4.  Role of hormones in mammary cancer initiation and progression.

Authors:  I H Russo; J Russo
Journal:  J Mammary Gland Biol Neoplasia       Date:  1998-01       Impact factor: 2.673

5.  Stat5a is mandatory for adult mammary gland development and lactogenesis.

Authors:  X Liu; G W Robinson; K U Wagner; L Garrett; A Wynshaw-Boris; L Hennighausen
Journal:  Genes Dev       Date:  1997-01-15       Impact factor: 11.361

6.  Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth.

Authors:  Carol A Sartorius; Djuana M E Harvell; Tianjie Shen; Kathryn B Horwitz
Journal:  Cancer Res       Date:  2005-11-01       Impact factor: 12.701

7.  Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.

Authors:  Patricia A Mote; Jennifer A Leary; Kelly A Avery; Kerstin Sandelin; Georgia Chenevix-Trench; Judy A Kirk; Christine L Clarke
Journal:  Genes Chromosomes Cancer       Date:  2004-03       Impact factor: 5.006

8.  Increased progesterone receptor expression in benign epithelium of BRCA1-related breast cancers.

Authors:  Tari A King; Mary L Gemignani; Weiwei Li; Dilip D Giri; Kathy S Panageas; Faina Bogomolniy; Crispinita Arroyo; Narciso Olvera; Mark E Robson; Kenneth Offit; Patrick I Borgen; Jeff Boyd
Journal:  Cancer Res       Date:  2004-08-01       Impact factor: 12.701

9.  Cell proliferation in normal human breast ducts, fibroadenomas, and other ductal hyperplasias measured by nuclear labeling with tritiated thymidine. Effects of menstrual phase, age, and oral contraceptive hormones.

Authors:  J S Meyer
Journal:  Hum Pathol       Date:  1977-01       Impact factor: 3.466
View more
  25 in total

1.  Increased High Molecular Weight FGF2 in Endocrine-Resistant Breast Cancer.

Authors:  Ana Sahores; Virginia Figueroa; María May; Marcos Liguori; Adrián Rubstein; Cynthia Fuentes; Britta M Jacobsen; Andrés Elía; Paola Rojas; Gonzalo R Sequeira; Michelle M Álvarez; Pedro González; Hugo Gass; Stephen Hewitt; Alfredo Molinolo; Claudia Lanari; Caroline A Lamb
Journal:  Horm Cancer       Date:  2018-06-28       Impact factor: 3.869

2.  Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells.

Authors:  Aaron K Holley; Kelley K Kiningham; Douglas R Spitz; Dean P Edwards; Jeffrey T Jenkins; Michael R Moore
Journal:  J Steroid Biochem Mol Biol       Date:  2009-06-27       Impact factor: 4.292

Review 3.  Progesterone action in breast, uterine, and ovarian cancers.

Authors:  Caroline H Diep; Andrea R Daniel; Laura J Mauro; Todd P Knutson; Carol A Lange
Journal:  J Mol Endocrinol       Date:  2015-01-13       Impact factor: 5.098

4.  Steroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation.

Authors:  A Silvina Nacht; Miguel Beato; Guillermo P Vicent
Journal:  Transcription       Date:  2016-10-04

5.  The chemopreventive effect of mifepristone on mammary tumorigenesis is associated with an anti-invasive and anti-inflammatory gene signature.

Authors:  Hongyan Yuan; Geeta Upadhyay; Jin Lu; Levy Kopelovich; Robert I Glazer
Journal:  Cancer Prev Res (Phila)       Date:  2012-03-16

6.  Progesterone induces expression of the prolactin receptor gene through cooperative action of Sp1 and C/EBP.

Authors:  Anita S Goldhar; Renqin Duan; Erika Ginsburg; Barbara K Vonderhaar
Journal:  Mol Cell Endocrinol       Date:  2011-01-14       Impact factor: 4.102

7.  Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression.

Authors:  J J Peluso; X Liu; A Gawkowska; V Lodde; C A Wu
Journal:  Mol Cell Endocrinol       Date:  2010-02-06       Impact factor: 4.102

8.  Progesterone receptor action: defining a role in breast cancer.

Authors:  Andrea R Daniel; Christy R Hagan; Carol A Lange
Journal:  Expert Rev Endocrinol Metab       Date:  2011-05-01

9.  Mammary Gland Evaluation in Juvenile Toxicity Studies: Temporal Developmental Patterns in the Male and Female Harlan Sprague-Dawley Rat.

Authors:  Adam J Filgo; Julie F Foley; Samantha Puvanesarajah; Aditi R Borde; Bentley R Midkiff; Casey E Reed; Vesna A Chappell; Lydia B Alexander; Pretish R Borde; Melissa A Troester; Schantel A Hayes Bouknight; Suzanne E Fenton
Journal:  Toxicol Pathol       Date:  2016-09-09       Impact factor: 1.902

Review 10.  The breast cancer and the environment research centers: transdisciplinary research on the role of the environment in breast cancer etiology.

Authors:  Robert A Hiatt; Sandra Z Haslam; Janet Osuch
Journal:  Environ Health Perspect       Date:  2009-06-16       Impact factor: 9.031
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.