OBJECTIVE: To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN). METHOD: Using Kaplan-Meier methods and Cox proportional hazards models, comparisons were conducted that were conditional on duration of eating disorder from onset and included a conservative recovery criterion of 3 asymptomatic years. Data collection was retrospective and from two of the international Price Foundation genetic studies on 901 individuals with eating disorders. RESULTS: Using Kaplan-Meier methods, 11% of those with index AN and 10% of those with index BN met recovery criteria at 10 years. At 15 years, 16% of those with index AN and 25% of those with index BN met recovery criteria. In a Cox proportional hazards model the index BN group had three times the rate of recovery at 10-14 years (p=0.01) than the index AN group. CONCLUSIONS: Initially the probability of recovery was greater for those with index AN, but as the duration of the eating disorder lengthened those with BN had higher probabilities of recovery. Replication of these results with prospective data using similarly stringent recovery criteria and methods is required to confirm trends.
OBJECTIVE: To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN). METHOD: Using Kaplan-Meier methods and Cox proportional hazards models, comparisons were conducted that were conditional on duration of eating disorder from onset and included a conservative recovery criterion of 3 asymptomatic years. Data collection was retrospective and from two of the international Price Foundation genetic studies on 901 individuals with eating disorders. RESULTS: Using Kaplan-Meier methods, 11% of those with index AN and 10% of those with index BN met recovery criteria at 10 years. At 15 years, 16% of those with index AN and 25% of those with index BN met recovery criteria. In a Cox proportional hazards model the index BN group had three times the rate of recovery at 10-14 years (p=0.01) than the index AN group. CONCLUSIONS: Initially the probability of recovery was greater for those with index AN, but as the duration of the eating disorder lengthened those with BN had higher probabilities of recovery. Replication of these results with prospective data using similarly stringent recovery criteria and methods is required to confirm trends.
Authors: Cinnamon S Bloss; Wade Berrettini; Andrew W Bergen; Pierre Magistretti; Vikas Duvvuri; Michael Strober; Harry Brandt; Steve Crawford; Scott Crow; Manfred M Fichter; Katherine A Halmi; Craig Johnson; Allan S Kaplan; Pamela Keel; Kelly L Klump; James Mitchell; Janet Treasure; D Blake Woodside; Enrica Marzola; Nicholas J Schork; Walter H Kaye Journal: Neuropsychopharmacology Date: 2011-07-13 Impact factor: 7.853
Authors: Stephanie Zerwas; Brian C Lund; Ann Von Holle; Laura M Thornton; Wade H Berrettini; Harry Brandt; Steven Crawford; Manfred M Fichter; Katherine A Halmi; Craig Johnson; Allan S Kaplan; Maria La Via; James Mitchell; Alessandro Rotondo; Michael Strober; D Blake Woodside; Walter H Kaye; Cynthia M Bulik Journal: J Psychiatr Res Date: 2013-03-25 Impact factor: 4.791
Authors: Anna M Bardone-Cone; Megan B Harney; Christine R Maldonado; Melissa A Lawson; D Paul Robinson; Roma Smith; Aneesh Tosh Journal: Behav Res Ther Date: 2009-11-13
Authors: Sarah Maguire; Lois J Surgenor; Daniel Le Grange; Hubert Lacey; Ross D Crosby; Scott G Engel; Kirsty M Fromholtz; Bryony Bamford; Stephen Touyz Journal: J Eat Disord Date: 2017-11-27