Literature DB >> 18195694

Calcium, cyclic AMP, and MAP kinases: dysregulation in polycystic kidney disease.

B D Cowley1.   

Abstract

Low intracellular calcium, present in untreated polycystic kidney epithelia, results in a proliferative response to cyclic adenosine monophosphate. Treatment with a calcium channel blocker (CCB) caused exacerbation of autosomal dominant polycystic kidney disease in rats. Data regarding use of CCBs in human polycystic kidney disease (PKD) are limited and mixed. Thus, it is premature to extrapolate these findings to human PKD.

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Year:  2008        PMID： 18195694     DOI： 10.1038/sj.ki.5002695

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  17 in total

1.  Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway.

Authors:  Netty G Santoso; Liudmila Cebotaru; William B Guggino
Journal:  Cell Physiol Biochem       Date:  2011-06-17

Review 2.  Autophagy and regulation of cilia function and assembly.

Authors:  I Orhon; N Dupont; O Pampliega; A M Cuervo; P Codogno
Journal:  Cell Death Differ       Date:  2014-10-31       Impact factor: 15.828

3.  Regulation of the Ste20-like kinase, SLK: involvement of activation segment phosphorylation.

Authors:  Artem Y Luhovy; Aala Jaberi; Joan Papillon; Julie Guillemette; Andrey V Cybulsky
Journal:  J Biol Chem       Date:  2011-12-27       Impact factor: 5.157

Review 4.  ADPKD-what the radiologist should know.

Authors:  Pritika Gaur; Wladyslaw Gedroyc; Peter Hill
Journal:  Br J Radiol       Date:  2019-04-30       Impact factor: 3.039

5.  Dietary phosphate restriction attenuates polycystic kidney disease in mice.

Authors:  Faith Omede; Shiqin Zhang; Cassandra Johnson; Emily Daniel; Yan Zhang; Timothy A Fields; Joseph Boulanger; Shiguang Liu; Ishfaq Ahmed; Shahid Umar; Darren Paul Wallace; Jason R Stubbs
Journal:  Am J Physiol Renal Physiol       Date:  2019-11-04

Review 6.  Cyclic AMP-mediated cyst expansion.

Authors:  Darren P Wallace
Journal:  Biochim Biophys Acta       Date:  2010-11-28

7.  Chronic treatment with lisinopril decreases proliferative and apoptotic pathways in autosomal recessive polycystic kidney disease.

Authors:  Guangfu Jia; Michelle Kwon; Huan Ling Liang; Jordan Mortensen; Vani Nilakantan; William E Sweeney; Frank Park
Journal:  Pediatr Nephrol       Date:  2010-03-13       Impact factor: 3.714

Review 8.  Calcium-mediated mechanisms of cystic expansion.

Authors:  Shakila Abdul-Majeed; Surya M Nauli
Journal:  Biochim Biophys Acta       Date:  2010-10-12

9.  Inactivation of max-interacting protein 1 induces renal cilia disassembly through reduction in levels of intraflagellar transport 20 in polycystic kidney.

Authors:  Je Yeong Ko; Kyung Hyun Yoo; Seon Ah Song; Do Yeon Kim; Hyun Kyung Kong; Curie Ahn; Han Woong Lee; Duk-Hee Kang; Goo Taeg Oh; Jong Hoon Park
Journal:  J Biol Chem       Date:  2013-01-13       Impact factor: 5.157

10.  The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function.

Authors:  María del Rocío Cantero; Irina F Velázquez; Andrew J Streets; Albert C M Ong; Horacio F Cantiello
Journal:  J Biol Chem       Date:  2015-08-12       Impact factor: 5.157
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