Pulmonary arterial hypertension.

It is important for the general internist to maintain a high degree of suspicion for pulmonary hypertension in appropriate cases. This article reviews the definition and classification of pulmonary hypertension, epidemiology and risk factors, signs and symptoms, diagnostic approach, and treatment strategies. Multiple effective therapies now exist for pulmonary arterial hypertension, and thus early diagnosis and referral will translate into meaningful survival and better lives for our patients.