Literature DB >> 18194671

Vascular versus myocardial dysfunction in acute coronary syndrome: are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification?

Peter A Kavsak1, Dennis T Ko, Alice M Newman, Viliam Lustig, Glenn E Palomaki, Andrew R MacRae, Allan S Jaffe.   

Abstract

OBJECTIVES: To determine if elevations of adhesion molecules in acute coronary syndrome (ACS) are useful for risk stratification. DESIGN AND METHODS: A cell adhesion array (Randox Ltd.) and NT-proBNP were measured in 216 ACS patients.
RESULTS: Kaplan-Meier and Cox models indicate early elevations of NT-proBNP but not the adhesion molecules are predictive of future death/myocardial infarction. DISCUSSION: Elevations of adhesion molecules early after pain onset in ACS are not useful for long-term risk stratification.

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Year:  2007        PMID： 18194671      PMCID： PMC3569501          DOI： 10.1016/j.clinbiochem.2007.12.010

Source DB:  PubMed          Journal:  Clin Biochem        ISSN： 0009-9120            Impact factor:   3.281


  11 in total

Review 1.  Vascular adhesion molecules in atherosclerosis.

Authors:  Elena Galkina; Klaus Ley
Journal:  Arterioscler Thromb Vasc Biol       Date:  2007-08-02       Impact factor: 8.311

2.  Comparative impact of multiple biomarkers and N-Terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) Study.

Authors:  Stefan Blankenberg; Matthew J McQueen; Marek Smieja; Janice Pogue; Cynthia Balion; Eva Lonn; Hans J Rupprecht; Christoph Bickel; Laurence Tiret; Francois Cambien; Hertzel Gerstein; Thomas Münzel; Salim Yusuf
Journal:  Circulation       Date:  2006-07-10       Impact factor: 29.690

3.  Long-term health outcomes associated with detectable troponin I concentrations.

Authors:  Peter A Kavsak; Alice M Newman; Viliam Lustig; Andrew R MacRae; Glenn E Palomaki; Dennis T Ko; Jack V Tu; Allan S Jaffe
Journal:  Clin Chem       Date:  2007-01-04       Impact factor: 8.327

Review 4.  Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome.

Authors:  Fred S Apple; Alan H B Wu; Johannes Mair; Jan Ravkilde; Mauro Panteghini; Jillian Tate; Franca Pagani; Robert H Christenson; Martin Mockel; Oliver Danne; Allan S Jaffe
Journal:  Clin Chem       Date:  2005-03-17       Impact factor: 8.327

5.  Relation between soluble intercellular adhesion molecule-1, statin therapy, and long-term risk of clinical cardiovascular events in patients with previous acute coronary syndrome (from PROVE IT-TIMI 22).

Authors:  Kausik K Ray; David A Morrow; Amy Shui; Nader Rifai; Christopher P Cannon
Journal:  Am J Cardiol       Date:  2006-08-04       Impact factor: 2.778

6.  Multiple biomarker use for detection of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome.

Authors:  Fred S Apple; Lesly A Pearce; Adrine Chung; Ranka Ler; MaryAnn M Murakami
Journal:  Clin Chem       Date:  2007-03-23       Impact factor: 8.327

7.  Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis.

Authors:  I Malik; J Danesh; P Whincup; V Bhatia; O Papacosta; M Walker; L Lennon; A Thomson; D Haskard
Journal:  Lancet       Date:  2001-09-22       Impact factor: 79.321

8.  Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure.

Authors:  Peter A Kavsak; Andrew R MacRae; Alice M Newman; Viliam Lustig; Glenn E Palomaki; Dennis T Ko; Jack V Tu; Allan S Jaffe
Journal:  Clin Biochem       Date:  2007-01-05       Impact factor: 3.281

9.  A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario.

Authors:  Peter C Austin; Paul A Daly; Jack V Tu
Journal:  Am Heart J       Date:  2002-08       Impact factor: 4.749

10.  Risk stratification for heart failure and death in an acute coronary syndrome population using inflammatory cytokines and N-terminal pro-brain natriuretic peptide.

Authors:  Peter A Kavsak; Dennis T Ko; Alice M Newman; Glenn E Palomaki; Viliam Lustig; Andrew R MacRae; Allan S Jaffe
Journal:  Clin Chem       Date:  2007-10-11       Impact factor: 8.327
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  1 in total

1.  PAPP-A as a marker of increased long-term risk in patients with chest pain.

Authors:  Peter A Kavsak; Xuesong Wang; Matthew Henderson; Dennis T Ko; Andrew R MacRae; Allan S Jaffe
Journal:  Clin Biochem       Date:  2009-03-25       Impact factor: 3.281
  1 in total

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