| Literature DB >> 18194647 |
Abstract
The AAA ATPase Vps4 disassembles the membrane-bound ESCRT-III lattice. Four recent publications show how Vps4 carries out this task in a partnership with another ESCRT-associated protein, Vta1. Vps4 and Vta1 both contain MIT domains, which bind to "MIT-interacting motifs" (MIMs) of ESCRT-III proteins. As new MIT domain proteins are rapidly being identified, these studies will likely have relevance well beyond Vps4.Entities:
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Year: 2008 PMID： 18194647 DOI： 10.1016/j.devcel.2007.12.013
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270