| Literature DB >> 18194646 |
Abstract
Wntless is a sorting receptor required for Wnt secretion. Wntless is retrieved from endosomes to the Golgi by retromer, permitting Wntless reutilization in Wnt transport. In the absence of retromer, Wntless is degraded in lysosomes and Wnt secretion is impaired.Mesh:
Substances:
Year: 2008 PMID: 18194646 DOI: 10.1016/j.devcel.2007.12.014
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270