Literature DB >> 18194354

Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation.

Orli Megged1, Itamar Shalit, Isaac Yaniv, Jerry Stein, Salvador Fisher, Itzhak Levy.   

Abstract

We describe a case of breakthrough cerebral toxoplasmosis during atovaquone therapy in a child who was intolerant of conventional prophylactic regimens after hematopoietic stem cell transplantation. The available data on the efficacy of atovaquone prophylaxis in Toxoplasma sero-positive stem cell transplant recipients remain limited, and other strategies, such as preemptive strategy using toxoplasma PCR or TMP-SMX desensitization should be considered in this setting.

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Year:  2008        PMID: 18194354     DOI: 10.1111/j.1399-3046.2007.00891.x

Source DB:  PubMed          Journal:  Pediatr Transplant        ISSN: 1397-3142


  6 in total

1.  Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds.

Authors:  Danièle Maubon; Alexandre Bougdour; Yung-Sing Wong; Marie-Pierre Brenier-Pinchart; Aurélie Curt; Mohamed-Ali Hakimi; Hervé Pelloux
Journal:  Antimicrob Agents Chemother       Date:  2010-08-16       Impact factor: 5.191

2.  Synthesis and evaluation of oryzalin analogs against Toxoplasma gondii.

Authors:  Molla M Endeshaw; Catherine Li; Jessica de Leon; Ni Yao; Kirk Latibeaudiere; Kokku Premalatha; Naomi Morrissette; Karl A Werbovetz
Journal:  Bioorg Med Chem Lett       Date:  2010-07-08       Impact factor: 2.823

Review 3.  Disseminated toxoplasmosis in non-allografted patients with hematologic malignancies: report of two cases and literature review.

Authors:  S Scerra; H Coignard-Biehler; F Lanternier; F Suarez; C Charlier-Woerther; M-E Bougnoux; J Gilquin; M Lecuit; O Hermine; O Lortholary
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-04-18       Impact factor: 3.267

4.  Artemisone and artemiside control acute and reactivated toxoplasmosis in a murine model.

Authors:  Ildiko R Dunay; Wing Chi Chan; Richard K Haynes; L David Sibley
Journal:  Antimicrob Agents Chemother       Date:  2009-07-27       Impact factor: 5.191

Review 5.  Activities of anti-Toxoplasma drugs and compounds against tissue cysts in the last three decades (1987 to 2017), a systematic review.

Authors:  Mahbobeh Montazeri; Saeed Mehrzadi; Mehdi Sharif; Shahabeddin Sarvi; Shayesteh Shahdin; Ahmad Daryani
Journal:  Parasitol Res       Date:  2018-08-08       Impact factor: 2.289

6.  Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.

Authors:  Joshua B Radke; Bruno Melillo; Payal Mittal; Manmohan Sharma; Amit Sharma; Yong Fu; Taher Uddin; Arthur Gonse; Eamon Comer; Stuart L Schreiber; Anil K Gupta; Arnab K Chatterjee; L David Sibley
Journal:  Nat Commun       Date:  2022-01-24       Impact factor: 17.694

  6 in total

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