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Literature DB >> 18193341

Inflammatory manifestations in chronic granulomatous disease (CGD).

Abstract

Chronic granulomatous disease (CGD) is a genetically heterogeneous disease characterized by recurrent life-threatening infections with bacteria and fungi as well as dysregulated inflammatory mechanisms. CGD is caused by defects in the NADPH oxidase, the enzyme complex responsible for generation of superoxide and other reactive oxygen species (ROS) in phagocytic cells. In this review we will focus our attention on those particular inflammatory manifestations associated with CGD, their frequencies and the underlying immunologic mechanisms favoring it occurrence.

Entities: Chemical Disease Gene

Mesh：

Substances：
NADPH Oxidases

Year: 2008 PMID： 18193341 DOI： 10.1007/s10875-007-9160-5

Source DB: PubMed Journal: J Clin Immunol ISSN： 0271-9142 Impact factor: 8.317

31 in total

1. Development of systemic lupus erythematosus in a young child affected with chronic granulomatous disease following withdrawal of treatment with interferon-gamma.

Authors: R Badolato; L D Notarangelo; A Plebani; D Roos
Journal: Rheumatology (Oxford) Date: 2003-06 Impact factor: 7.580

2. Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

Authors: Brahm H Segal; Bruce A Davidson; Alan D Hutson; Thomas A Russo; Bruce A Holm; Barbara Mullan; Michael Habitzruther; Steven M Holland; Paul R Knight
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2006-11-17 Impact factor: 5.464

3. Successful treatment of refractory autoimmune thrombocytopenia with rituximab and cyclosporin A in a patient with chronic granulomatous disease.

Authors: Jacek Treliński; Krzysztof Chojnowski; Magdalena Kurenko-Deptuch; Marek Kasznicki; Ewa Bernatowska; Tadeusz Robak
Journal: Ann Hematol Date: 2005-11-12 Impact factor: 3.673

Review 4. The urological manifestations of chronic granulomatous disease.

Authors: M M Walther; H Malech; A Berman; P Choyke; D J Venzon; W M Linehan; J I Gallin
Journal: J Urol Date: 1992-05 Impact factor: 7.450

5. Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B.

Authors: Johan Bylund; Kelly L MacDonald; Kelly L Brown; Piotr Mydel; L Vincent Collins; Robert E W Hancock; David P Speert
Journal: Eur J Immunol Date: 2007-04 Impact factor: 5.532

6. Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD).

Authors: Joanne R Brown; David Goldblatt; Joanna Buddle; Louise Morton; Adrian J Thrasher
Journal: J Leukoc Biol Date: 2003-05 Impact factor: 4.962

7. Gene expression profiling provides insight into the pathophysiology of chronic granulomatous disease.

Authors: Scott D Kobayashi; Jovanka M Voyich; Kevin R Braughton; Adeline R Whitney; William M Nauseef; Harry L Malech; Frank R DeLeo
Journal: J Immunol Date: 2004-01-01 Impact factor: 5.422

8. Recurrent cystitis and bladder mass in two adults with chronic granulomatous disease.

Authors: F S Southwick; J W van der Meer
Journal: Ann Intern Med Date: 1988-07-15 Impact factor: 25.391

9. Hemophagocytic syndrome and Burkholderia cepacia splenic microabscesses in a child with chronic granulomatous disease.

Authors: Sayomporn Sirinavin; Chonnamet Techasaensiri; Samart Pakakasama; Malai Vorachit; Rattanaporn Pornkul; Rames Wacharasin
Journal: Pediatr Infect Dis J Date: 2004-09 Impact factor: 2.129

Review 10. Cytokines in autoimmune disorders.

Authors: M Feldmann; F M Brennan; R Maini
Journal: Int Rev Immunol Date: 1998 Impact factor: 5.311

42 in total

1. Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.

Authors: Colleen J Lewis; Brian A Cobb
Journal: Eur J Immunol Date: 2011-08-04 Impact factor: 5.532

Inflammatory manifestations in chronic granulomatous disease (CGD).

1. Development of systemic lupus erythematosus in a young child affected with chronic granulomatous disease following withdrawal of treatment with interferon-gamma.

2. Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

3. Successful treatment of refractory autoimmune thrombocytopenia with rituximab and cyclosporin A in a patient with chronic granulomatous disease.

Review 4. The urological manifestations of chronic granulomatous disease.

5. Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B.

6. Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD).

7. Gene expression profiling provides insight into the pathophysiology of chronic granulomatous disease.

8. Recurrent cystitis and bladder mass in two adults with chronic granulomatous disease.

9. Hemophagocytic syndrome and Burkholderia cepacia splenic microabscesses in a child with chronic granulomatous disease.

Review 10. Cytokines in autoimmune disorders.

1. Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.

2. Monocyte/macrophage-specific NADPH oxidase contributes to antimicrobial host defense in X-CGD.

Review 3. Newcomers in paediatric GI pathology: childhood enteropathies including very early onset monogenic IBD.

Review 4. Recent insights into the pathobiology of innate immune deficiencies.

Review 5. Gene therapy of chronic granulomatous disease: the engraftment dilemma.

6. p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis.

7. Regulatory T cell features in chronic granulomatous disease.

8. Orthopaedic case of the month: Painless right knee mass in 32-year-old man.

Review 9. Copper homeostasis at the host-pathogen interface.

10. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.