INTRODUCTION: Fractures are a considerable public health burden in the United Kingdom but information on their epidemiology is limited. OBJECTIVE: This study aims to estimate the true annual incidence and lifetime prevalence of fractures in England, within both the general population and specific groups, using a self-report methodology. METHODS: A self-report survey of a nationally representative general population sample of 45,293 individuals in England, plus a special boost sample of 10,111 drawn from the ethnic minority population. RESULTS: The calculated fracture incidence is 3.6 fractures per 100 people per year. Lifetime fracture prevalence exceeds 50% in middle-aged men, and 40% in women over the age of 75 years. Fractures occur with reduced frequency in the non-white population: this effect is seen across most black and minority ethnic groups. CONCLUSIONS: This study suggests that fractures in England may be more common than previously estimated, with an overall annual fracture incidence of 3.6%. Age-standardised lifetime fracture prevalence is estimated to be 38.2%. Fractures are more commonplace in the white population.
INTRODUCTION:Fractures are a considerable public health burden in the United Kingdom but information on their epidemiology is limited. OBJECTIVE: This study aims to estimate the true annual incidence and lifetime prevalence of fractures in England, within both the general population and specific groups, using a self-report methodology. METHODS: A self-report survey of a nationally representative general population sample of 45,293 individuals in England, plus a special boost sample of 10,111 drawn from the ethnic minority population. RESULTS: The calculated fracture incidence is 3.6 fractures per 100 people per year. Lifetime fracture prevalence exceeds 50% in middle-aged men, and 40% in women over the age of 75 years. Fractures occur with reduced frequency in the non-white population: this effect is seen across most black and minority ethnic groups. CONCLUSIONS: This study suggests that fractures in England may be more common than previously estimated, with an overall annual fracture incidence of 3.6%. Age-standardised lifetime fracture prevalence is estimated to be 38.2%. Fractures are more commonplace in the white population.
Authors: Babette S Zemel; Heidi J Kalkwarf; Vicente Gilsanz; Joan M Lappe; Sharon Oberfield; John A Shepherd; Margaret M Frederick; Xiangke Huang; Ming Lu; Soroosh Mahboubi; Thomas Hangartner; Karen K Winer Journal: J Clin Endocrinol Metab Date: 2011-09-14 Impact factor: 5.958
Authors: K Siggeirsdottir; T Aspelund; B Y Jonsson; B Mogensen; E F Gudmundsson; V Gudnason; G Sigurdsson Journal: Osteoporos Int Date: 2013-07-02 Impact factor: 4.507
Authors: Julie Bruce; Anower Hossain; Ranjit Lall; Emma J Withers; Susanne Finnegan; Martin Underwood; Chen Ji; Chris Bojke; Roberta Longo; Claire Hulme; Susie Hennings; Ray Sheridan; Katharine Westacott; Shvaita Ralhan; Finbarr Martin; John Davison; Fiona Shaw; Dawn A Skelton; Jonathan Treml; Keith Willett; Sarah E Lamb Journal: Health Technol Assess Date: 2021-05 Impact factor: 4.014
Authors: Dirk Vanderschueren; Michaël R Laurent; Frank Claessens; Evelien Gielen; Marie K Lagerquist; Liesbeth Vandenput; Anna E Börjesson; Claes Ohlsson Journal: Endocr Rev Date: 2014-09-09 Impact factor: 19.871