| Literature DB >> 18192068 |
Abstract
Using Arabidopsis microRNA (miRNA)-mediated gene regulation system as a model, we investigated how complex systems evolve with special attention to selection to maintain the systems. We found that the copy number of miRNA genes within each system is a key factor to determine the complexity of the system, indicating a crucial role of gene duplication to increase the complexity. Furthermore, we show that the mode of selection to maintain the systems depend on their complexity levels.Entities:
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Year: 2008 PMID： 18192068 DOI： 10.1016/j.tig.2007.11.002
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639