| Literature DB >> 18191217 |
Abstract
The long-awaited structure of the effector portion of IRE1, the endoplasmic reticulum stress transducer, is published in this issue of Cell (Lee et al., 2008). This structure provides new insight into the mysterious coupling of kinase and endoribonuclease activities in the oldest, most-conserved branch of the unfolded protein response in eukaryotes.Entities:
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Year: 2008 PMID: 18191217 DOI: 10.1016/j.cell.2007.12.017
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582