Literature DB >> 18190954

Diagnosis and management of HIV drug hypersensitivity.

Carla M Davis1, William T Shearer.   

Abstract

Drug hypersensitivity reactions are an important cause of morbidity in HIV-infected patients who take complex medication regimens. Correct diagnosis and management of these reactions are essential in the clinical care of HIV disease. Trimethoprim-sulfamethoxazole, abacavir, nevirapine, atazanavir, and enfuvirtide can all cause hypersensitivity rashes. In this review, we discuss the evidence for immunologic mechanisms of hypersensitivity reactions to HIV medications, the clinical characteristics of these reactions, and guidelines that currently exist for their identification and management.

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Year:  2008        PMID： 18190954     DOI： 10.1016/j.jaci.2007.10.021

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


  15 in total

Review 1.  Analysis of current antifungal agents and their targets within the Pneumocystis carinii genome.

Authors:  Aleksey Porollo; Jaroslaw Meller; Yogesh Joshi; Vikash Jaiswal; A George Smulian; Melanie T Cushion
Journal:  Curr Drug Targets       Date:  2012-11       Impact factor: 3.465

Review 2.  Hypersensitivity reactions to HIV therapy.

Authors:  Mas Chaponda; Munir Pirmohamed
Journal:  Br J Clin Pharmacol       Date:  2011-05       Impact factor: 4.335

3.  Evaluation of sulfonamide detoxification pathways in haematologic malignancy patients prior to intermittent trimethoprim-sulfamethoxazole prophylaxis.

Authors:  Mahmoud Abouraya; James C Sacco; Brad S Kahl; Lauren A Trepanier
Journal:  Br J Clin Pharmacol       Date:  2011-04       Impact factor: 4.335

4.  Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV.

Authors:  Brittany Elizabeth Yee; Nghia Hoang Nguyen; Daniel Lee
Journal:  BMJ Case Rep       Date:  2014-05-05

5.  Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents.

Authors:  George K Siberry; Erin Leister; Denise L Jacobson; Samuel B Foster; George R Seage; Steven E Lipshultz; Mary E Paul; Murli Purswani; Andrew A Colin; Gwendolyn Scott; William T Shearer
Journal:  Clin Immunol       Date:  2011-10-30       Impact factor: 3.969

6.  HIV Tat potentiates cell toxicity in a T cell model for sulphamethoxazole-induced adverse drug reactions.

Authors:  Kemi Adeyanju; Adriana Krizova; Philippe A Gilbert; Gregory A Dekaban; Michael Rieder
Journal:  Virus Genes       Date:  2009-03-10       Impact factor: 2.332

Review 7.  PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2.

Authors:  Ellen M McDonagh; Sotiria Boukouvala; Eleni Aklillu; David W Hein; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2014-08       Impact factor: 2.089

Review 8.  Secondary immunodeficiencies, including HIV infection.

Authors:  Javier Chinen; William T Shearer
Journal:  J Allergy Clin Immunol       Date:  2009-12-29       Impact factor: 10.793

9.  Prevalence of abacavir-associated hypersensitivity syndrome and HLA-B*5701 allele in a Portuguese HIV-positive population.

Authors:  Fabrícia Carolino; Natacha Santos; Carmela Piñeiro; Ana Sofia Santos; Pedro Soares; António Sarmento; Josefina Rodrigues Cernadas
Journal:  Porto Biomed J       Date:  2017-02-04

10.  Clinical applications of drug desensitization in the Asia-Pacific region.

Authors:  Bernard Yu-Hor Thong
Journal:  Asia Pac Allergy       Date:  2011-04-26
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