Literature DB >> 18188484

A cleavable linker strategy for optimising enolate alkylation reactions of a polymer-supported Evans' oxazolidin-2-one.

Rachel Green1, Andrew T Merritt, Steven D Bull.   

Abstract

A cleavable linker strategy has been used to optimise the enolate alkylation reactions of a recyclable L-tyrosine derived polymer-supported oxazolidin-2-one for the asymmetric synthesis of a series of chiral alpha-alkyl acids.

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Year:  2007        PMID： 18188484     DOI： 10.1039/b713966g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Lithium Amino Alkoxide-Evans Enolate Mixed Aggregates: Aldol Addition with Matched and Mismatched Stereocontrol.

Authors:  Janis Jermaks; Evan H Tallmadge; Ivan Keresztes; David B Collum
Journal:  J Am Chem Soc       Date:  2018-02-19       Impact factor: 15.419

2.  Solid-phase asymmetric synthesis using a polymer-supported chiral Evans'-type oxazolidin-2-one.

Authors:  Rachel Green; Jennifer Peed; James E Taylor; Richard A R Blackburn; Steven D Bull
Journal:  Nat Protoc       Date:  2013-09-12       Impact factor: 13.491

3.  Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions.

Authors:  Quynh Pham Bao Nguyen; Taek Hyeon Kim
Journal:  Beilstein J Org Chem       Date:  2013-10-15       Impact factor: 2.883
  3 in total

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