BACKGROUND: Pulmonary vascular resistance (PVR) is a critical parameter in the assessment and treatment of patients with pulmonary hypertension, regardless of origin. Noninvasive estimation of PVR could be helpful. METHODS: Consecutive patients with known or suggested pulmonary hypertension referred for cardiac catheterization were evaluated prospectively and the PVR was calculated invasively. Subsequently, the tricuspid regurgitation velocity (TRV), the velocity-time integral (mean of 3 measurements) of the right ventricular outflow tract (VTIm), and the right ventricular outflow tract diameter were recorded noninvasively. RESULTS: The TRV/VTIm ratio and the TRV/VTIm corrected for the indexed RVOT diameter correlated well with the PVR at catheterization with R(2) = 0.711 and R(2) = 0.731, respectively, including patients with very high values of PVR. A TRV/VTI(RVOT) value of 38 provided a specificity of 100% for a PVR of 8 Woods units. CONCLUSION: Noninvasive estimation is feasible over a broad range of PVR values and could be a useful tool to estimate and longitudinally tracked changes in PVR.
BACKGROUND: Pulmonary vascular resistance (PVR) is a critical parameter in the assessment and treatment of patients with pulmonary hypertension, regardless of origin. Noninvasive estimation of PVR could be helpful. METHODS: Consecutive patients with known or suggested pulmonary hypertension referred for cardiac catheterization were evaluated prospectively and the PVR was calculated invasively. Subsequently, the tricuspid regurgitation velocity (TRV), the velocity-time integral (mean of 3 measurements) of the right ventricular outflow tract (VTIm), and the right ventricular outflow tract diameter were recorded noninvasively. RESULTS: The TRV/VTIm ratio and the TRV/VTIm corrected for the indexed RVOT diameter correlated well with the PVR at catheterization with R(2) = 0.711 and R(2) = 0.731, respectively, including patients with very high values of PVR. A TRV/VTI(RVOT) value of 38 provided a specificity of 100% for a PVR of 8 Woods units. CONCLUSION: Noninvasive estimation is feasible over a broad range of PVR values and could be a useful tool to estimate and longitudinally tracked changes in PVR.
Authors: Martin Koestenberger; Mark K Friedberg; Eirik Nestaas; Ina Michel-Behnke; Georg Hansmann Journal: Pulm Circ Date: 2016-03 Impact factor: 3.017
Authors: Juha W Koskenvuo; Rachel Mirsky; Yan Zhang; Franca S Angeli; Sarah Jahn; Tero-Pekka Alastalo; Nelson B Schiller; Andrew J Boyle; Kanu Chatterjee; Teresa De Marco; Yerem Yeghiazarians Journal: Int J Cardiovasc Imaging Date: 2010-02-07 Impact factor: 2.357
Authors: Alexander R Opotowsky; Mathieu Clair; Jonathan Afilalo; Michael J Landzberg; Aaron B Waxman; Lilamarie Moko; Bradley A Maron; Anjali Vaidya; Paul R Forfia Journal: Am J Cardiol Date: 2013-06-01 Impact factor: 2.778