Literature DB >> 18186774

Prevalence and characteristics of left ventricular noncompaction in a community hospital cohort of patients with systolic dysfunction.

Roopinder Sandhu1, Robert S Finkelhor, Diyana R Gunawardena, Robert C Bahler.   

Abstract

BACKGROUND: Left ventricular noncompaction (LVNC) is felt to be a rare form of cardiomyopathy, although its prevalence in a nonreferred population is unknown. We examined the prevalence and clinical characteristics of LVNC in a community hospital cohort of adult patients with echocardiographic evidence of left ventricular (LV) systolic dysfunction.
METHODS: All adult echocardiograms with global LV dysfunction and an LVEF < or = 45% over a 1-year period were reviewed for signs of LV noncompaction. Its presence was confirmed by the consensus of at least 2/3 readers specifically searching for this using standard criteria for noncompaction.
RESULTS: A 3.7% prevalence of definite or probable LVNC was found in those with LVEF < or = 45% and a 0.26% prevalence for all patients referred for echocardiography during this period. This is appreciably higher than prior reports from tertiary centers.
CONCLUSION: Noncompaction may not be a rare phenomenon and is comparable to other more widely recognized but less common causes of heart failure such as peripartum myopathy, connective tissue diseases, chronic substance abuse and HIV disease.

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Year:  2008        PMID: 18186774     DOI: 10.1111/j.1540-8175.2007.00560.x

Source DB:  PubMed          Journal:  Echocardiography        ISSN: 0742-2822            Impact factor:   1.724


  21 in total

Review 1.  Isolated non-compaction cardiomyopathy.

Authors:  Rolf Engberding; Claudia Stöllberger; Peter Ong; Talat M Yelbuz; Birgit J Gerecke; Günter Breithardt
Journal:  Dtsch Arztebl Int       Date:  2010-03-26       Impact factor: 5.594

Review 2.  Genetics of inherited cardiomyopathy.

Authors:  Daniel Jacoby; William J McKenna
Journal:  Eur Heart J       Date:  2011-08-02       Impact factor: 29.983

3.  Biventricular noncompaction cardiomyopathy with malignant arrhythmia as a cause of sudden death.

Authors:  Petr Handlos; Tomáš Gruszka; Marie Staňková; Klára Marecová; Marek Joukal
Journal:  Forensic Sci Med Pathol       Date:  2017-06-15       Impact factor: 2.007

4.  Clinical significance of right ventricular dysfunction in left ventricular non-compaction cardiomyopathy.

Authors:  Steve W Leung; Claude-Samy Elayi; Richard J Charnigo; Mushabbar A Syed
Journal:  Int J Cardiovasc Imaging       Date:  2011-07-27       Impact factor: 2.357

5.  [Isolated noncompaction cardiomyopathy with special emphasis on arrhythmia complications].

Authors:  B Gerecke; R Engberding
Journal:  Herzschrittmacherther Elektrophysiol       Date:  2012-09-25

6.  Analysis of ventricular hypertrabeculation and noncompaction using genetically engineered mouse models.

Authors:  Hanying Chen; Wenjun Zhang; Deqiang Li; Tim M Cordes; R Mark Payne; Weinian Shou
Journal:  Pediatr Cardiol       Date:  2009-04-25       Impact factor: 1.655

Review 7.  Left Ventricular Non-Compaction in Athletes: To Play or Not to Play.

Authors:  Eric Emmanuel Coris; Byron Keith Moran; Raymond De Cuba; Ted Farrar; Anne B Curtis
Journal:  Sports Med       Date:  2016-09       Impact factor: 11.136

Review 8.  Molecular mechanism of ventricular trabeculation/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC).

Authors:  Wenjun Zhang; Hanying Chen; Xiuxia Qu; Ching-Pin Chang; Weinian Shou
Journal:  Am J Med Genet C Semin Med Genet       Date:  2013-07-10       Impact factor: 3.908

9.  Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity.

Authors:  Hanying Chen; Wenjun Zhang; Xiaoxin Sun; Momoko Yoshimoto; Zhuang Chen; Wuqiang Zhu; Jijia Liu; Yadan Shen; Weidong Yong; Deqiang Li; Jin Zhang; Yang Lin; Baiyan Li; Nathan J VanDusen; Paige Snider; Robert J Schwartz; Simon J Conway; Loren J Field; Mervin C Yoder; Anthony B Firulli; Nadia Carlesso; Jeffrey A Towbin; Weinian Shou
Journal:  Development       Date:  2013-05       Impact factor: 6.868

10.  Sudden cardiac arrest as the initial presentation for left ventricular noncompaction cardiomyopathy.

Authors:  Avaneesh Jakkoju; Rakesh Jakkoju; Vishnupriya Kuchana; Pedro R Cox-Alomar; Frank W Smart; D Luke Glancy
Journal:  Proc (Bayl Univ Med Cent)       Date:  2019-07-31
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