Literature DB >> 18186388

Excess mortality, length of stay, and costs associated with serious hemorrhage among trauma patients: findings from the National Trauma Data Bank.

Luke Boulanger1, Ashish V Joshi, Bartholomew J Tortella, Joseph Menzin, John P Caloyeras, Mason W Russell.   

Abstract

Trauma is a serious injury or shock to the body from violence or crash and is an important and growing global health risk. Using 2000 to 2004 data from a comprehensive trauma registry, we estimated the prevalence of serious blunt and penetrating trauma-related hemorrhage among patients admitted to U.S. trauma centers along with excess in-hospital mortality, length of hospital stay, and inpatient costs. There were 65,750 patients with blunt trauma and 12,992 patients with penetrating trauma included in our analyses. Of patients sustaining blunt trauma, 7.6 per cent had serious hemorrhage; 18.8 per cent of patients sustaining penetrating trauma had serious hemorrhage. In-hospital mortality rates were significantly (P < 0.05) higher for patients with serious hemorrhage than for patients without (24.9 per cent versus 8.4 per cent for blunt; 23.4 per cent versus 4.2 per cent for penetrating). Patients with serious hemorrhage had adjusted mean excess lengths of stay of 0.4 days for blunt trauma and 2.7 days for penetrating trauma (P < 0.05); adjusted excess costs were $296 per day for patients sustaining blunt trauma and $637 per day for patients sustaining penetrating trauma (P < 0.05). In both blunt and penetrating trauma cases, serious hemorrhage is significantly associated with excess mortality, longer hospital stays, and higher costs.

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Year:  2007        PMID: 18186388

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  8 in total

1.  Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats.

Authors:  Lei Qi; Xiaoxuan Cui; Weifeng Dong; Rafael Barrera; Jeffrey Nicastro; Gene F Coppa; Ping Wang; Rongqian Wu
Journal:  Mol Med       Date:  2012-03-27       Impact factor: 6.354

2.  Peroxisome proliferator activated receptor-γ and traumatic brain injury.

Authors:  Lei Qi; Asha Jacob; Ping Wang; Rongqian Wu
Journal:  Int J Clin Exp Med       Date:  2010-09-23

Review 3.  Influence of the National Trauma Data Bank on the study of trauma outcomes: is it time to set research best practices to further enhance its impact?

Authors:  Adil H Haider; Taimur Saleem; Jeffrey J Leow; Cassandra V Villegas; Mehreen Kisat; Eric B Schneider; Elliott R Haut; Kent A Stevens; Edward E Cornwell; Ellen J MacKenzie; David T Efron
Journal:  J Am Coll Surg       Date:  2012-02-07       Impact factor: 6.113

4.  Estrogen suppresses cardiac IL-6 after trauma-hemorrhage via a hypoxia-inducible factor 1 alpha-mediated pathway.

Authors:  Eike A Nickel; Chi-Hsun Hsieh; Jianguo G Chen; Martin G Schwacha; Irshad H Chaudry
Journal:  Shock       Date:  2009-04       Impact factor: 3.454

Review 5.  Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial.

Authors:  Katharine Ker; Junko Kiriya; Pablo Perel; Phil Edwards; Haleema Shakur; Ian Roberts
Journal:  BMC Emerg Med       Date:  2012-03-01

6.  β2-adrenergic regulation of stress hyperglycemia following hemorrhage in the obese Zucker rat.

Authors:  John S Clemmer; Lusha Xiang; Silu Lu; Peter N Mittwede; Robert L Hester
Journal:  Physiol Rep       Date:  2014-12-03

7.  Effect of acute hypoxemia on cerebral blood flow velocity control during lower body negative pressure.

Authors:  Noud van Helmond; Blair D Johnson; Walter W Holbein; Humphrey G Petersen-Jones; Ronée E Harvey; Sushant M Ranadive; Jill N Barnes; Timothy B Curry; Victor A Convertino; Michael J Joyner
Journal:  Physiol Rep       Date:  2018-02

8.  The effect of discharge destination and primary insurance provider on hospital discharge delays among patients with traumatic brain injury: a multicenter study of 1,543 patients.

Authors:  Melissa Sorensen; Erica Sercy; Kristin Salottolo; Michael Waxman; Thomas A West; Allen Tanner; David Bar-Or
Journal:  Patient Saf Surg       Date:  2020-01-06
  8 in total

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