Literature DB >> 18184753

Putting to rest the myth of creatine supplementation leading to muscle cramps and dehydration.

V J Dalbo1, M D Roberts, J R Stout, C M Kerksick.   

Abstract

Creatine is one of the most popular athletic supplements with sales surpassing 400 million dollars in 2004. Due to the popularity and efficacy of creatine supplementation over 200 studies have examined the effects of creatine on athletic performance. Despite the abundance of research suggesting the effectiveness and safety of creatine, a fallacy appears to exist among the general public, driven by media claims and anecdotal reports, that creatine supplementation can result in muscle cramps and dehydration. Although a number of published studies have refuted these claims, a recent position statement by the American College of Sports Medicine (ACSM) in 2000 advised individuals who are managing their weight and exercising intensely or in hot environments to avoid creatine supplementation. Recent reports now suggest that creatine may enhance performance in hot and/or humid conditions by maintaining haematocrit, aiding thermoregulation and reducing exercising heart rate and sweat rate. Creatine may also positively influence plasma volume during the onset of dehydration. Considering these new published findings, little evidence exists that creatine supplementation in the heat presents additional risk, and this should be taken into consideration as position statements and other related documents are published.

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Year:  2008        PMID: 18184753     DOI: 10.1136/bjsm.2007.042473

Source DB:  PubMed          Journal:  Br J Sports Med        ISSN: 0306-3674            Impact factor:   13.800


  16 in total

1.  Creatine supplementation does not impair kidney function in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial.

Authors:  Bruno Gualano; Vitor de Salles Painelli; Hamilton Roschel; Rebeca Lugaresi; Egidio Dorea; Guilherme Giannini Artioli; Fernanda Rodrigues Lima; Maria Elizabeth Rossi da Silva; Maria Rosária Cunha; Antonio Carlos Seguro; Maria Heloisa Shimizu; Maria Concepción García Otaduy; Marcelo Tatit Sapienza; Cláudia da Costa Leite; Eloisa Bonfá; Antonio Herbert Lancha Junior
Journal:  Eur J Appl Physiol       Date:  2010-10-26       Impact factor: 3.078

Review 2.  Does creatine supplementation hinder exercise heat tolerance or hydration status? A systematic review with meta-analyses.

Authors:  Rebecca M Lopez; Douglas J Casa; Brendon P McDermott; Matthew S Ganio; Lawrence E Armstrong; Carl M Maresh
Journal:  J Athl Train       Date:  2009 Mar-Apr       Impact factor: 2.860

Review 3.  ISSN exercise & sports nutrition review update: research & recommendations.

Authors:  Chad M Kerksick; Colin D Wilborn; Michael D Roberts; Abbie Smith-Ryan; Susan M Kleiner; Ralf Jäger; Rick Collins; Mathew Cooke; Jaci N Davis; Elfego Galvan; Mike Greenwood; Lonnie M Lowery; Robert Wildman; Jose Antonio; Richard B Kreider
Journal:  J Int Soc Sports Nutr       Date:  2018-08-01       Impact factor: 5.150

Review 4.  Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

Authors:  Patricia J Allen
Journal:  Neurosci Biobehav Rev       Date:  2012-03-24       Impact factor: 8.989

5.  Chronic creatine supplementation alters depression-like behavior in rodents in a sex-dependent manner.

Authors:  Patricia J Allen; Kristen E D'Anci; Robin B Kanarek; Perry F Renshaw
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

Review 6.  Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults.

Authors:  Scott C Forbes; Darren G Candow; Sergej M Ostojic; Michael D Roberts; Philip D Chilibeck
Journal:  Nutrients       Date:  2021-06-02       Impact factor: 5.717

7.  Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats.

Authors:  Ryan G Toedebusch; Thomas E Childs; Shari R Hamilton; Jan R Crowley; Frank W Booth; Michael D Roberts
Journal:  J Int Soc Sports Nutr       Date:  2012-06-06       Impact factor: 5.150

8.  A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate.

Authors:  Adam Sanchez; Elfego Galvan; James Fluckey; Steven Riechman; Michael Greenwood; Katherine Kelly; Cynthia Meininger; Christopher Rasmussen; Andrew R Jagim; Jonathan M Oliver; Richard B Kreider
Journal:  J Int Soc Sports Nutr       Date:  2012-09-13       Impact factor: 5.150

9.  Creatine supplementation with specific view to exercise/sports performance: an update.

Authors:  Robert Cooper; Fernando Naclerio; Judith Allgrove; Alfonso Jimenez
Journal:  J Int Soc Sports Nutr       Date:  2012-07-20       Impact factor: 5.150

Review 10.  Analysis of the efficacy, safety, and regulatory status of novel forms of creatine.

Authors:  Ralf Jäger; Martin Purpura; Andrew Shao; Toshitada Inoue; Richard B Kreider
Journal:  Amino Acids       Date:  2011-03-22       Impact factor: 3.520

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