Literature DB >> 18184001

Aplaminal: a novel cytotoxic aminal isolated from the sea hare Aplysia kurodai.

Takeshi Kuroda1, Hideo Kigoshi.   

Abstract

Aplaminal (1), a novel triazabicyclo[3.2.1]octane framework metabolite, has been isolated from the sea hare Aplysia kurodai. The structure was determined by analysis of NMR data and confirmed by single-crystal X-ray diffraction analysis. Aplaminal (1) exhibits cytotoxicity against Hela S3 cells.

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Year:  2008        PMID： 18184001     DOI： 10.1021/ol7029307

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

Review 1.  Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.

Authors:  Maria Letizia Ciavatta; Florence Lefranc; Marianna Carbone; Ernesto Mollo; Margherita Gavagnin; Tania Betancourt; Ramesh Dasari; Alexander Kornienko; Robert Kiss
Journal:  Med Res Rev       Date:  2016-12-07       Impact factor: 12.944

Review 2.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

3.  Facile Access to Ring-Fused Aminals via Direct α-Amination of Secondary Amines with ortho-Aminobenzaldehydes. Synthesis of Vasicine, Deoxyvasicine, Deoxyvasicinone, Mackinazolinone and Ruteacarpine.

Authors:  Matthew T Richers; Indubhusan Deb; Alena Yu Platonova; Chen Zhang; Daniel Seidel
Journal:  Synthesis (Stuttg)       Date:  2013-10-06       Impact factor: 3.157

4.  Total synthesis of (-)-aplaminal.

Authors:  Amos B Smith; Zhuqing Liu
Journal:  Org Lett       Date:  2008-08-28       Impact factor: 6.005

5.  Metal-free α-amination of secondary amines: computational and experimental evidence for azaquinone methide and azomethine ylide intermediates.

Authors:  Arne Dieckmann; Matthew T Richers; Alena Yu Platonova; Chen Zhang; Daniel Seidel; K N Houk
Journal:  J Org Chem       Date:  2013-04-02       Impact factor: 4.354

Review 6.  Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus.

Authors:  Renato B Pereira; Paula B Andrade; Patrícia Valentão
Journal:  Mar Drugs       Date:  2016-02-19       Impact factor: 5.118
  6 in total

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