| Literature DB >> 18182260 |
Vivek K Gupta1, Atiya Fatima, Uzma Faridi, Arvind S Negi, Karuna Shanker, J K Kumar, Neha Rahuja, Suaib Luqman, Brijesh S Sisodia, Dharmendra Saikia, M P Darokar, Suman P S Khanuja.
Abstract
The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.Entities:
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Year: 2007 PMID： 18182260 DOI： 10.1016/j.jep.2007.11.037
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360