BACKGROUND: Most psychosocial risk factors appear to have general rather than specific patterns of association with common childhood and adolescence disorders. However, previous research has typically failed to 1) control for comorbidity among disorders, 2) include a wide range of risk factors, and 3) examine sex by developmental stage effects on risk factor-disorder associations. This study tests the specificity of putative psychosocial risk factors while addressing these criticisms. METHODS: Eight waves of data from the Great Smoky Mountains Study (N = 1,420) were used, covering children in the community age 9-16 years old. Youth and one parent were interviewed up to seven times using the Child and Adolescent Psychiatric Assessment, providing a total of 6,674 pairs of interviews. A wide range of putative neighborhood, school, peer, family, and child risk factors, and common and comorbid youth disorders were assessed. RESULTS: The majority of putative risk factors were specific to one disorder or one disorder domain. A unique or 'signature set' of putative risk factors was identified for each disorder. Several putative risk factors were associated with a disorder in preadolescent males, preadolescent females, adolescent males, or adolescent females only. CONCLUSIONS: Our findings support the need to define risk factors and disorders narrowly, to control comorbidity and other risk factors, and to consider developmental patterns of specificity by sex.
BACKGROUND: Most psychosocial risk factors appear to have general rather than specific patterns of association with common childhood and adolescence disorders. However, previous research has typically failed to 1) control for comorbidity among disorders, 2) include a wide range of risk factors, and 3) examine sex by developmental stage effects on risk factor-disorder associations. This study tests the specificity of putative psychosocial risk factors while addressing these criticisms. METHODS: Eight waves of data from the Great Smoky Mountains Study (N = 1,420) were used, covering children in the community age 9-16 years old. Youth and one parent were interviewed up to seven times using the Child and Adolescent Psychiatric Assessment, providing a total of 6,674 pairs of interviews. A wide range of putative neighborhood, school, peer, family, and child risk factors, and common and comorbid youth disorders were assessed. RESULTS: The majority of putative risk factors were specific to one disorder or one disorder domain. A unique or 'signature set' of putative risk factors was identified for each disorder. Several putative risk factors were associated with a disorder in preadolescent males, preadolescent females, adolescent males, or adolescent females only. CONCLUSIONS: Our findings support the need to define risk factors and disorders narrowly, to control comorbidity and other risk factors, and to consider developmental patterns of specificity by sex.
Authors: Ronald C Kessler; Katie A McLaughlin; Jennifer Greif Green; Michael J Gruber; Nancy A Sampson; Alan M Zaslavsky; Sergio Aguilar-Gaxiola; Ali Obaid Alhamzawi; Jordi Alonso; Matthias Angermeyer; Corina Benjet; Evelyn Bromet; Somnath Chatterji; Giovanni de Girolamo; Koen Demyttenaere; John Fayyad; Silvia Florescu; Gilad Gal; Oye Gureje; Josep Maria Haro; Chi-Yi Hu; Elie G Karam; Norito Kawakami; Sing Lee; Jean-Pierre Lépine; Johan Ormel; José Posada-Villa; Rajesh Sagar; Adley Tsang; T Bedirhan Ustün; Svetlozar Vassilev; Maria Carmen Viana; David R Williams Journal: Br J Psychiatry Date: 2010-11 Impact factor: 9.319
Authors: Christina J M Colletti; Rex Forehand; Emily Garai; Laura McKee; Jennifer Potts; Kelly Haker; Jennifer Champion; Bruce E Compas Journal: J Child Fam Stud Date: 2010-12
Authors: Michelle G Newman; Sandra J Llera; Thane M Erickson; Amy Przeworski; Louis G Castonguay Journal: Annu Rev Clin Psychol Date: 2013 Impact factor: 18.561