| Literature DB >> 18179166 |
Lucia De Monte1, Francesca Sanvito, Stefano Olivieri, Fiammetta Viganò, Claudio Doglioni, Matteo Frasson, Marco Braga, Angela Bachi, Paolo Dellabona, Maria Pia Protti, Massimo Alessio.
Abstract
Sera from colon carcinoma patients were used to identify tumor-associated antigens (TAAs) by screening tumor proteome resolved by 2D electrophoresis. A panel of six TAAs eliciting a serological immune response in colorectal cancer was identified, showing a modification in antigen recognition by B cells in patients as a function of colon cancer progression. The expression of these proteins was either confined or increased in tumor as compared to normal mucosa.Entities:
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Year: 2008 PMID: 18179166 DOI: 10.1021/pr070360m
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466