Literature DB >> 18178686

Hepatocellular carcinoma associated with recreational anabolic steroid use.

P Gorayski1, C H Thompson, H S Subhash, A C Thomas.   

Abstract

A 35-year-old male bodybuilder was found to have a hepatocellular carcinoma (HCC) arising in a pre-existing hepatic adenoma following recreational anabolic steroid use. Given the widespread use of recreational anabolic steroids, another potentially life-threatening complication is highlighted in addition to the more commonly recognised hepatic adenoma. Malignant transformation to HCC from a pre-existing hepatic adenoma confirmed by immunohistochemical study has previously not been reported in athletes taking anabolic steroids. Further studies using screening programmes to identify high-risk individuals are recommended.

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Year:  2008        PMID： 18178686     DOI： 10.1136/bjsm.2007.03932

Source DB:  PubMed          Journal:  Br J Sports Med        ISSN： 0306-3674            Impact factor:   13.800


  17 in total

Review 1.  Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: a looming public health concern?

Authors:  Gen Kanayama; James I Hudson; Harrison G Pope
Journal:  Drug Alcohol Depend       Date:  2008-07-02       Impact factor: 4.492

Review 2.  Benign solid tumors of the liver: management in the modern era.

Authors:  Georgios Antonios Margonis; Aslam Ejaz; Gaya Spolverato; Neda Rastegar; Robert Anders; Ihab R Kamel; Timothy M Pawlik
Journal:  J Gastrointest Surg       Date:  2015-01-06       Impact factor: 3.452

3.  Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion.

Authors:  Junping Ao; Jiao Meng; Lei Zhu; Huizhen Nie; Chenchen Yang; Jinjun Li; Jianren Gu; Qiushi Lin; Weiwen Long; Xiaoqun Dong; Chao Li
Journal:  Mol Oncol       Date:  2012-07-05       Impact factor: 6.603

Review 4.  Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement.

Authors:  Harrison G Pope; Ruth I Wood; Alan Rogol; Fred Nyberg; Larry Bowers; Shalender Bhasin
Journal:  Endocr Rev       Date:  2013-12-17       Impact factor: 19.871

Review 5.  Malignant transformation of hepatocellular adenomas into hepatocellular carcinomas: a systematic review including more than 1600 adenoma cases.

Authors:  Jan H M B Stoot; Robert J S Coelen; Mechteld C De Jong; Cornelis H C Dejong
Journal:  HPB (Oxford)       Date:  2010-10       Impact factor: 3.647

Review 6.  Illicit anabolic-androgenic steroid use.

Authors:  Gen Kanayama; James I Hudson; Harrison G Pope
Journal:  Horm Behav       Date:  2009-09-18       Impact factor: 3.587

7.  Anabolic steroid abuse causing recurrent hepatic adenomas and hemorrhage.

Authors:  Nicole M Martin; Barham K Abu Dayyeh; Raymond T Chung
Journal:  World J Gastroenterol       Date:  2008-07-28       Impact factor: 5.742

8.  Relevance of low testosterone to non-alcoholic fatty liver disease.

Authors:  Avni Mody; Donna White; Fasiha Kanwal; Jose M Garcia
Journal:  Cardiovasc Endocrinol       Date:  2015-09-01

9.  Hepatocellular adenoma in a woman who was undergoing testosterone treatment for gender identity disorder.

Authors:  Keizo Kato; Hiroshi Abe; Noriko Hanawa; Junya Fukuzawa; Ryota Matsuo; Takeshi Yonezawa; Sadahiro Itoh; Yoshiyuki Sato; Makiko Ika; Shohei Shimizu; Shinji Endo; Hiroshi Hano; Asami Izu; Masahiko Sugitani; Akihito Tsubota
Journal:  Clin J Gastroenterol       Date:  2018-03-27

10.  Development of hepatocellular carcinoma associated with anabolic androgenic steroid abuse in a young bodybuilder: a case report.

Authors:  Aline Hardt; Dirk Stippel; Margarete Odenthal; Arnulf H Hölscher; Hans-Peter Dienes; Uta Drebber
Journal:  Case Rep Pathol       Date:  2012-07-05
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