Literature DB >> 18177952

Perinatal administration of PCP alters adult behaviour in female Sprague-Dawley rats.

Teresa Marie du Bois1, Xu-Feng Huang, Chao Deng.   

Abstract

Perinatal phencyclidine (PCP) treatment leads to neuronal damage and causes long-term behavioural alterations in rodents. This study examined the effects of perinatal PCP treatment on behaviour of adult rats in holeboard, elevated plus maze, social interaction and forced swim tests. PCP-treated rats displayed hyperactivity in the holeboard and forced swim tests. These persistent behavioural changes are relevant to the study of psychiatric disorders such as schizophrenia.

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Year:  2007        PMID: 18177952     DOI: 10.1016/j.bbr.2007.11.017

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN: 0166-4328            Impact factor:   3.332


  7 in total

1.  Effect of clozapine on locomotor activity and anxiety-related behavior in the neonatal mice administered MK-801.

Authors:  Neslihan Pınar; Kubra Akillioglu; Fatih Sefil; Harun Alp; Mustafa Sagir; Ahmet Acet
Journal:  Bosn J Basic Med Sci       Date:  2015-08-11       Impact factor: 3.363

Review 2.  Models of neurodevelopmental abnormalities in schizophrenia.

Authors:  Susan B Powell
Journal:  Curr Top Behav Neurosci       Date:  2010

3.  Improved Social Interaction, Recognition and Working Memory with Cannabidiol Treatment in a Prenatal Infection (poly I:C) Rat Model.

Authors:  Ashleigh L Osborne; Nadia Solowij; Ilijana Babic; Xu-Feng Huang; Katrina Weston-Green
Journal:  Neuropsychopharmacology       Date:  2017-02-23       Impact factor: 7.853

4.  Altered dopamine receptor and dopamine transporter binding and tyrosine hydroxylase mRNA expression following perinatal NMDA receptor blockade.

Authors:  Teresa Marie du Bois; Ching-Wen Hsu; Yulin Li; Yean Yeow Tan; Chao Deng; Xu-Feng Huang
Journal:  Neurochem Res       Date:  2008-02-08       Impact factor: 3.996

5.  Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex.

Authors:  Tariq W Chohan; An Nguyen; Stephanie M Todd; Maxwell R Bennett; Paul Callaghan; Jonathon C Arnold
Journal:  Front Behav Neurosci       Date:  2014-09-29       Impact factor: 3.558

6.  Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats.

Authors:  Jessica L Andrews; Kelly A Newell; Natalie Matosin; Xu-Feng Huang; Francesca Fernandez
Journal:  Neuronal Signal       Date:  2018-09-28

7.  In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia.

Authors:  Somayeh Jafari; Xu-Feng Huang; Jessica L Andrews; Francesca Fernandez-Enright
Journal:  PLoS One       Date:  2013-12-11       Impact factor: 3.240

  7 in total

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