OBJECTIVE: Decreased bone mineral density (BMD) in anorexia nervosa (AN) can be detected easily by dual-energy X-ray absorptiometry (DXA). This study was designed to assess the prevalence of osteoporosis and osteopenia in AN, identify predictors, and determine the diagnostic yield of screening with DXA. METHOD: DXA was used to screen 59 unselected adult patients with a history of AN. RESULTS: Osteoporosis was identified in 18 patients (31%) and osteopenia in 30 (51%). The spine had a lower mean T-score than either the hip or femur. BMI significantly predicted T-score (p = 0.0006) and the odds of having osteoporosis (p = 0.0188). There was a significant association between use of oestrogens and the presence of osteoporosis or osteopenia (p = 0.0491). There was no significant association between duration of AN and T-score. A duration of AN of less than 1 year was found in 12% of those with osteoporosis. CONCLUSION: BMI is a strong predictor of BMD in AN. DXA is an effective screening tool and should probably be offered routinely. Copyright 2007 by Wiley Periodicals, Inc.
OBJECTIVE: Decreased bone mineral density (BMD) in anorexia nervosa (AN) can be detected easily by dual-energy X-ray absorptiometry (DXA). This study was designed to assess the prevalence of osteoporosis and osteopenia in AN, identify predictors, and determine the diagnostic yield of screening with DXA. METHOD: DXA was used to screen 59 unselected adult patients with a history of AN. RESULTS:Osteoporosis was identified in 18 patients (31%) and osteopenia in 30 (51%). The spine had a lower mean T-score than either the hip or femur. BMI significantly predicted T-score (p = 0.0006) and the odds of having osteoporosis (p = 0.0188). There was a significant association between use of oestrogens and the presence of osteoporosis or osteopenia (p = 0.0491). There was no significant association between duration of AN and T-score. A duration of AN of less than 1 year was found in 12% of those with osteoporosis. CONCLUSION: BMI is a strong predictor of BMD in AN. DXA is an effective screening tool and should probably be offered routinely. Copyright 2007 by Wiley Periodicals, Inc.
Authors: Elizabeth Barron; Natalia Cano Sokoloff; Giovana D N Maffazioli; Kathryn E Ackerman; Ryan Woolley; Tara M Holmes; Ellen J Anderson; Madhusmita Misra Journal: J Acad Nutr Diet Date: 2015-12-11 Impact factor: 4.910
Authors: J Herrou; N Godart; A Etcheto; S Kolta; N Barthe; A Y Maugars; T Thomas; C Roux; K Briot Journal: Eat Weight Disord Date: 2020-10-21 Impact factor: 4.652