Literature DB >> 18175985

Cytotoxic constituents from the leaves of Cinnamomum subavenium.

Soong-Yu Kuo1, Tian-Jye Hsieh, Yau-Der Wang, Wen-Li Lo, Yen-Ray Hsui, Chung-Yi Chen.   

Abstract

Two new butanolides, subamolide D (1) and subamolide E (2), and a new secobutanolide, secosubamolide A (3), along with 21 known compounds were isolated from the leaves of Cinnamomum subavenium. The structures of 1-3 were determined by spectroscopic analysis. Propidium iodide staining and cytometry analysis were used to evaluate the cell cycle progression of the treated SW480 cells and it was found that 1 and 2 caused DNA damage in a dose- and time-dependent manner.

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Year:  2008        PMID： 18175985     DOI： 10.1248/cpb.56.97

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  5 in total

1.  Antiproliferative Compounds from Ocotea macrocarpa from the Madagascar Dry Forest1.

Authors:  Yixi Liu; Emily Cheng; L Harinantenaina Rakotondraibe; Peggy J Brodie; Wendy Applequist; Richard Randrianaivo; Andriamalala Rakotondrafara; Michel Ratsimbason; Vincent E Rasamison; David G I Kingston
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

2.  Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae).

Authors:  Thais A da Costa-Silva; Geanne A Alves Conserva; Andrés J Galisteo; Andre G Tempone; João Henrique G Lago
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2019-08-19

3.  Subamolide B Isolated from Medicinal Plant Cinnamomum subavenium Induces Cytotoxicity in Human Cutaneous Squamous Cell Carcinoma Cells through Mitochondrial and CHOP-Dependent Cell Death Pathways.

Authors:  Shu-Yi Yang; Hui-Min Wang; Tai-Wen Wu; Yi-Ju Chen; Jeng-Jer Shieh; Ju-Hwa Lin; Tsing-Fen Ho; Ren-Jie Luo; Chung-Yi Chen; Chia-Che Chang
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-13       Impact factor: 2.629

4.  Herbal Formulation C168 Attenuates Proliferation and Induces Apoptosis in HCT 116 Human Colorectal Carcinoma Cells: Role of Oxidative Stress and DNA Damage.

Authors:  Lek Mun Leong; Kok Meng Chan; Asmah Hamid; Jalifah Latip; Nor Fadilah Rajab
Journal:  Evid Based Complement Alternat Med       Date:  2016-01-17       Impact factor: 2.629

Review 5.  Chemical constituents and bioactivity of Formosan lauraceous plants.

Authors:  Hsun-Shuo Chang; Ih-Sheng Chen
Journal:  J Food Drug Anal       Date:  2016-01-05       Impact factor: 6.157
  5 in total

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