Literature DB >> 18175227

Dermatofibrosarcoma protuberans and small bowel adenocarcinoma: coincidental occurrence or genetic association?

Ashley Sumrall1, Nilam Soni.   

Abstract

A case of multiple malignancies in a 41 year old African American man is described. After surgical excision and radiotherapy of dermatofibrosarcoma protuberans, the patient developed small bowel adenocarcinoma. We propose a common etiology to these canceres via tumor suppressor gene p53.

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Year:  2006        PMID: 18175227     DOI: 10.1007/s12029-007-9000-0

Source DB:  PubMed          Journal:  Int J Gastrointest Cancer        ISSN: 1537-3649


  6 in total

1.  Dermatofibrosarcoma protuberans: an analysis of proliferative activity, DNA flow cytometry and p53 overexpression with emphasis on its progression.

Authors:  M Sasaki; T Ishida; H Horiuchi; R MacHinami
Journal:  Pathol Int       Date:  1999-09       Impact factor: 2.534

2.  Multiple epithelial and nonepithelial tumors in hereditary nonpolyposis colorectal cancer: characterization of germline and somatic mutations of the MSH2 gene and heterogeneity of replication error phenotypes.

Authors:  Rui-Len Huang; Chung-Faye Chao; Dah-Ching Ding; Cheng-Ping Yu; Cheng-Chang Chang; Hung-Chen Lai; Mu-Hsien Yu; Hang-Seng Liu; Tang-Yuan Chu
Journal:  Cancer Genet Cytogenet       Date:  2004-09

3.  p53 protein immunoreactivity in fibrohistiocytic tumors of the skin.

Authors:  C S Lee; S T Chou
Journal:  Pathology       Date:  1998-08       Impact factor: 5.306

4.  Dermatofibrosarcoma protuberans and breast cancer: genetic link or coincidental association?

Authors:  Derrick J Beech; Anne Brown Long; William Paul Long
Journal:  Am Surg       Date:  2004-06       Impact factor: 0.688

5.  Comparison of p53 expression in dermatofibrosarcoma protuberans and dermatofibroma: lack of correlation with proliferation rate.

Authors:  C Díaz-Cascajo; J Bastida-Iñarrea; L Borrego; G Carretero-Hernández
Journal:  J Cutan Pathol       Date:  1995-08       Impact factor: 1.587

6.  Immunohistochemical analysis of adenocarcinoma of the small intestine: a tissue microarray study.

Authors:  M Svrcek; F Jourdan; N Sebbagh; A Couvelard; D Chatelain; N Mourra; S Olschwang; D Wendum; J-F Fléjou
Journal:  J Clin Pathol       Date:  2003-12       Impact factor: 3.411

  6 in total

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