Literature DB >> 18175009

Mycothiol disulfide reductase: solid phase synthesis and evaluation of alternative substrate analogues.

Matthew J G Stewart1, Vishnu Karthik Jothivasan, Andrew S Rowan, Jennifer Wagg, Chris J Hamilton.   

Abstract

A solid phase synthesis of des-myo-inositol mycothiol disulfide and its alpha-configured methyl- and benzyl-glycoside derivatives has been developed. Kinetic characterisation of these compounds has demonstrated their viability as alternative substrates for use in mycothiol disulfide reductase enzyme assays.

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Year:  2007        PMID： 18175009     DOI： 10.1039/b716380k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Intramolecular alpha-glucosaminidation: synthesis of mycothiol.

Authors:  Kehinde Ajayi; Vinay V Thakur; Robert C Lapo; Spencer Knapp
Journal:  Org Lett       Date:  2010-06-04       Impact factor: 6.005

2.  Characterization of [4Fe-4S]-containing and cluster-free forms of Streptomyces WhiD.

Authors:  Jason C Crack; Chris D den Hengst; Piotr Jakimowicz; Sowmya Subramanian; Michael K Johnson; Mark J Buttner; Andrew J Thomson; Nick E Le Brun
Journal:  Biochemistry       Date:  2009-12-29       Impact factor: 3.162

Review 3.  Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria.

Authors:  Gerald L Newton; Nancy Buchmeier; Robert C Fahey
Journal:  Microbiol Mol Biol Rev       Date:  2008-09       Impact factor: 11.056

4.  QM/MM Study of the Fosfomycin Resistance Mechanism Involving FosB Enzyme.

Authors:  Anderson H Lima; José Rogério A Silva; Cláudio Nahum Alves; Jerônimo Lameira
Journal:  ACS Omega       Date:  2021-05-03

5.  NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function.

Authors:  Jason C Crack; John Munnoch; Erin L Dodd; Felicity Knowles; Mahmoud M Al Bassam; Saeed Kamali; Ashley A Holland; Stephen P Cramer; Chris J Hamilton; Michael K Johnson; Andrew J Thomson; Matthew I Hutchings; Nick E Le Brun
Journal:  J Biol Chem       Date:  2015-03-14       Impact factor: 5.157
  5 in total

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