Literature DB >> 18174992

Transferred-NOE NMR experiments on intact human platelets: receptor-bound conformation of RGD-peptide mimics.

Donatella Potenza1, Laura Belvisi.   

Abstract

The aim of this work is to show that transferred-NOE provides useful and detailed information on membrane-bound receptor-ligand interactions in living cells. Here, we study the interaction between intact human platelets and some ligands containing the RGD sequence. Conformational properties of the free and bound pentapeptides are reported.

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Year:  2007        PMID： 18174992     DOI： 10.1039/b713036h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Transferred NOESY NMR studies of biotin mimetic peptide (FSHPQNT) bound to streptavidin: a structural model for studies of peptide-protein interactions.

Authors:  Dawit Gizachew; Edward Dratz
Journal:  Chem Biol Drug Des       Date:  2011-05-26       Impact factor: 2.817

2.  Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies.

Authors:  Ileana Guzzetti; Monica Civera; Francesca Vasile; Daniela Arosio; Cristina Tringali; Umberto Piarulli; Cesare Gennari; Luca Pignataro; Laura Belvisi; Donatella Potenza
Journal:  ChemistryOpen       Date:  2016-12-09       Impact factor: 2.911

3.  NMR Characterization of Surface Receptor Protein Interactions in Live Cells Using Methylcellulose Hydrogels.

Authors:  Borja Mateos; Marco Sealey-Cardona; Katja Balazs; Judith Konrat; Guenther Staffler; Robert Konrat
Journal:  Angew Chem Int Ed Engl       Date:  2020-01-29       Impact factor: 15.336
  3 in total

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