Literature DB >> 18174773

Aortic dissection and third-degree atrioventricular block in a patient with a hypertensive crisis.

Nikolaos Lionakis1, Ioannis Moyssakis, Elias Gialafos, Nikolaos Dalianis, Vassilios Votteas.   

Abstract

A 55-year-old man with a history of uncontrolled hypertension was admitted because of an episode of severely elevated blood pressure. An electrocardiogram revealed complete atrioventricular block while imaging showed a dissecting aneurysm of the descending thoracic and abdominal aorta, type B according to the Stanford classification. Laboratory tests revealed significant increases in serum C-reactive protein. Coronary arteriography was performed and was negative for coronary artery disease. A VDD pacemaker was placed, and a combination of 4 antihypertensive agents was used as treatment. Type B aortic dissection may present with a wide range of manifestations. The authors suggest that measurement of C-reactive protein may be used in hypertensive patients to help reflect vascular injury and its degree, progression, and prognosis. Disorders of intraventricular conductivity are rarely seen in both types of dissection of the aorta (type A, B). Atrioventricular conductivity disorders that result in complete atrioventricular block have been reported only in patients with type A dissection (before the bifurcation of the subclavian artery). In this particular case, however, the authors diagnosed an atrioventricular conductivity disorder causing atrioventricular block in a patient with type B dissection. Consequently, the authors speculate that myocardial fibrosis, as a result of long-standing hypertension, could be the main pathogenetic mechanism leading to the development of such phenomena, resulting from a potential expanding of the fibrotic process to the atrioventricular conduction system.

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Year:  2008        PMID: 18174773      PMCID: PMC8110033          DOI: 10.1111/j.1524-6175.2007.07202.x

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN: 1524-6175            Impact factor:   3.738


  26 in total

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Journal:  Circulation       Date:  2003-09-09       Impact factor: 29.690

2.  Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease.

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3.  Acute phase proteins in patients with abdominal aortic aneurysms.

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5.  [Cardial fibrosis and the functional activity of leukocytes in patients with essential arterial hypertension].

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Review 6.  Clinical aspects of hypertensive myocardial fibrosis.

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Authors:  Ramón Querejeta; Begoña López; Arantxa González; Eloy Sánchez; Mariano Larman; José L Martínez Ubago; Javier Díez
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9.  Effect of C-reactive protein on chemokine expression in human aortic endothelial cells.

Authors:  Sridevi Devaraj; Pappanaicken R Kumaresan; Ishwarlal Jialal
Journal:  J Mol Cell Cardiol       Date:  2004-03       Impact factor: 5.000

10.  Human heart generates complement proteins that are upregulated and activated after myocardial infarction.

Authors:  K Yasojima; C Schwab; E G McGeer; P L McGeer
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  2 in total

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Authors:  Hidenori Fujiwara; Katsuo Matsuki
Journal:  Gen Thorac Cardiovasc Surg       Date:  2012-03-28

2.  Aortic aneurysm with complete atrioventricular block and acute coronary syndrome.

Authors:  Moacyr Magno Palmeira; Hellen Yuki Umemura Ribeiro; Yan Garcia Lira; Fernando Octávio Machado Jucá Neto; Ivone Aline da Silva Rodrigues; Maitê Silva Martins Gadelha; Yuri Santana do Carmo
Journal:  BMC Res Notes       Date:  2016-05-04
  2 in total

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