Literature DB >> 18173422

Favourable response to infliximab in a case of bilateral refractory Mooren's ulcer.

Luigi Fontana, Gabriella Parente, Piergiorgio Neri, Massimo Reta, Giorgio Tassinari.   

Abstract

A woman with progressive bilateral Mooren's ulcer developed recurrent corneal perforations and melting requiring tectonic grafts, despite conventional immunosuppressant therapy. Following treatment with infliximab, an anti-tumour necrosis factor agent, the patient showed marked reduction in conjunctival inflammation and no further recurrence of corneal thinning and perforation during 2-year follow up on maintaining treatment.

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Year:  2007        PMID: 18173422     DOI: 10.1111/j.1442-9071.2007.01609.x

Source DB:  PubMed          Journal:  Clin Exp Ophthalmol        ISSN: 1442-6404            Impact factor:   4.207


  7 in total

Review 1.  Biologic therapy for refractory scleritis: a new treatment perspective.

Authors:  Tania Sales de Alencar de Fidelix; Luis Antonio Vieira; Denise de Freitas; Virginia Fernandes Moça Trevisani
Journal:  Int Ophthalmol       Date:  2015-08-29       Impact factor: 2.031

2.  Peripheral ulcerative keratitis as the presenting feature of systemic rheumatoid vasculitis without joint involvement.

Authors:  Peter J Morgan-Warren; Simon Dulku; Jaya Ravindran; George Smith
Journal:  Int Ophthalmol       Date:  2014-08       Impact factor: 2.031

3.  Increased succinate receptor GPR91 involved in the pathogenesis of Mooren's ulcer.

Authors:  Lin Li; Yan-Ling Dong; Ting Liu; Dan Luo; Chao Wei; Wei-Yun Shi
Journal:  Int J Ophthalmol       Date:  2018-11-18       Impact factor: 1.779

4.  A rare case of peripheral ulcerative keratitis associated with Behçet's disease.

Authors:  Yong-Sok Ji; Kyung Chul Yoon
Journal:  Int Ophthalmol       Date:  2014-02-04       Impact factor: 2.031

5.  Stabilization of bilateral progressive rheumatoid corneal melt with infliximab.

Authors:  Sheelah F Antao; Tariq Ayoub; Hasan Tahir; Dipak N Parmar
Journal:  Case Rep Ophthalmol Med       Date:  2012-05-30

Review 6.  Infliximab for peripheral ulcerative keratitis treatment.

Authors:  Valentín Huerva; Francisco J Ascaso; Andrzej Grzybowski
Journal:  Medicine (Baltimore)       Date:  2014-11       Impact factor: 1.889

7.  Amniotic membrane transplantation ineffective as additional therapy in patients with aggressive Mooren's ulcer.

Authors:  Maurice Schallenberg; Henrike Westekemper; Klaus-Peter Steuhl; Daniel Meller
Journal:  BMC Ophthalmol       Date:  2013-12-17       Impact factor: 2.209

  7 in total

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