| Literature DB >> 18172635 |
Shiori Amemiya1, Masaaki Akahane, Junko Takita, Takashi Igarashi, Kuni Ohtomo.
Abstract
Acute megakaryoblastic leukaemia (AMKL), a relatively rare type of acute myeloid leukaemia, is characterized by frequent involvement of the liver, spleen and lymph nodes in addition to myelofibrosis in children. Diagnosis is difficult both clinically and pathologically, and the hepatic or lymph node involvement is not uncommonly misinterpreted as solid tumour. We report the imaging findings of upper abdominal involvement by AMKL in an infant. The hepatic lesion, initially suspected to be hepatoblastoma, showed a distinctive appearance on MRI suggesting its infiltrative nature. With the association of splenic lesion and lymphadenopathy, the imaging findings were considered indicative of a haematological disorder.Entities:
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Year: 2008 PMID: 18172635 DOI: 10.1007/s00247-007-0719-3
Source DB: PubMed Journal: Pediatr Radiol ISSN: 0301-0449