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Literature DB >> 18167314

Protein kinase C isozymes as therapeutic targets for treatment of human cancers.

Alan P Fields¹, Nicole R Murray.

Abstract

Entities: Disease Species

Mesh：

Substances：

Year: 2008 PMID： 18167314 PMCID： PMC2586109 DOI： 10.1016/j.advenzreg.2007.11.014

Source DB: PubMed Journal: Adv Enzyme Regul ISSN： 0065-2571

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64 in total

1. Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane.

Authors: M Takahashi; S Nakatsugi; T Sugimura; K Wakabayashi
Journal: Carcinogenesis Date: 2000-06 Impact factor: 4.944

2. Protein kinase C-alpha and -beta play antagonistic roles in the differentiation process of THP-1 cells.

Authors: P Dieter; H Schwende
Journal: Cell Signal Date: 2000-05 Impact factor: 4.315

3. Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.

Authors: Y Gökmen-Polar; N R Murray; M A Velasco; Z Gatalica; A P Fields
Journal: Cancer Res Date: 2001-02-15 Impact factor: 12.701

4. Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro.

Authors: H F Seung Kim; E J Weeber; J D Sweatt; A L Stoll; L B Marangell
Journal: Mol Psychiatry Date: 2001-03 Impact factor: 15.992

5. Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma.

Authors: Michael J Robertson; Brad S Kahl; Julie M Vose; Sven de Vos; Mary Laughlin; Patrick J Flynn; Kendrith Rowland; Jose C Cruz; Stuart L Goldberg; Luna Musib; Christelle Darstein; Nathan Enas; Jeffery L Kutok; Jon C Aster; Donna Neuberg; Kerry J Savage; Ann LaCasce; Donald Thornton; Christopher A Slapak; Margaret A Shipp
Journal: J Clin Oncol Date: 2007-03-26 Impact factor: 44.544

6. Morphodensitometric analysis of protein kinase C beta(II) expression in rat colon: modulation by diet and relation to in situ cell proliferation and apoptosis.

Authors: L A Davidson; R E Brown; W C Chang; J S Morris; N Wang; R J Carroll; N D Turner; J R Lupton; R S Chapkin
Journal: Carcinogenesis Date: 2000-08 Impact factor: 4.944

7. Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota.

Authors: Eda Erdogan; Trond Lamark; Melody Stallings-Mann; Maurizio Pellecchia; Mauricio Pellechia; E Aubrey Thompson; Terje Johansen; Alan P Fields
Journal: J Biol Chem Date: 2006-07-22 Impact factor: 5.157

8. Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ mice.

Authors: Henrik Oster; Michael Leitges
Journal: Cancer Res Date: 2006-07-15 Impact factor: 12.701

9. Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.

Authors: Lin Zhang; Jia Huang; Nuo Yang; Shun Liang; Andrea Barchetti; Antonis Giannakakis; Mark G Cadungog; Ann O'Brien-Jenkins; Marco Massobrio; Katherine F Roby; Dionyssios Katsaros; Phyllis Gimotty; Ralf Butzow; Barbara L Weber; George Coukos
Journal: Cancer Res Date: 2006-05-01 Impact factor: 12.701

10. Protein kinase C-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells.

Authors: Lingjie Guan; Kyung Song; Marybeth A Pysz; Kathryn J Curry; A Asli Hizli; David Danielpour; Adrian R Black; Jennifer D Black
Journal: J Biol Chem Date: 2007-03-13 Impact factor: 5.157

20 in total

Review 1. Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors.

Authors: Andrea Comba; Yi-Hui Lin; Aldo Renato Eynard; Mirta Ana Valentich; Martín Ernesto Fernandez-Zapico; Marìa Eugenia Pasqualini
Journal: Cancer Metastasis Rev Date: 2011-12 Impact factor: 9.264

Review 2. Atypical protein kinase Cι as a human oncogene and therapeutic target.

Authors: Peter J Parker; Verline Justilien; Philippe Riou; Mark Linch; Alan P Fields
Journal: Biochem Pharmacol Date: 2013-11-11 Impact factor: 5.858

Review 3. The roles of PKCs in regulating autophagy.

Authors: Tianyi Wang; Conghe Liu; Lili Jia
Journal: J Cancer Res Clin Oncol Date: 2018-08-16 Impact factor: 4.553

4. The chromosome 3q26 OncCassette: A multigenic driver of human cancer.

Authors: Alan P Fields; Verline Justilien; Nicole R Murray
Journal: Adv Biol Regul Date: 2015-12-23

5. A Gynecologic Oncology Group phase II trial of the protein kinase C-beta inhibitor, enzastaurin and evaluation of markers with potential predictive and prognostic value in persistent or recurrent epithelial ovarian and primary peritoneal malignancies.

Authors: Lydia Usha; Michael W Sill; Kathleen M Darcy; Doris M Benbrook; Jean A Hurteau; David P Michelin; Robert S Mannel; Parviz Hanjani; Koen De Geest; Andrew K Godwin
Journal: Gynecol Oncol Date: 2011-03-17 Impact factor: 5.482