Literature DB >> 18166188

Motivation to donate or not donate surplus embryos for stem-cell research: literature review.

Kristina Hug1.   

Abstract

OBJECTIVE: To review publications regarding possible donation of surplus embryos for medical research.
DESIGN: Review of 67 scientific publications in this field up through January 2007. ORIGINALITY: Summary of factors influencing prospective donors' motivation to donate or not donate their surplus embryos for medical research. RESULT(S): Presentation of the findings of studies regarding the need and availability of quality human embryos for stem-cell research, discussion of the use of nonoptimal quality embryos for research, and presentation of the findings of several studies regarding the attitudes of fertility patients toward embryo donation for research in general and for stem-cell research in particular. In addition, discussion of the difficulty of such decision making and presentation of suggested strategies to facilitate reasoned, reflective, and timely decisions by prospective donors. CONCLUSION(S): The major part of this article presents the findings of studies regarding the factors influencing couples' decisions about whether or not to donate surplus embryos for research. Research purpose, treatment stage, embryo quality, religious beliefs, and altruism appear to be important for donation. Being at the beginning of treatment, not knowing the aim of medical research, or having good-quality embryos appear to motivate those who answer that they do not want to donate.

Entities:  

Mesh:

Year:  2007        PMID: 18166188     DOI: 10.1016/j.fertnstert.2007.09.017

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  12 in total

1.  Correcting misperceptions about cryopreserved embryos and stem cell research.

Authors:  Geoffrey P Lomax; Alan O Trounson
Journal:  Nat Biotechnol       Date:  2013-04       Impact factor: 54.908

2.  Recent trends in embryo disposition choices made by patients following in vitro fertilization.

Authors:  Vinita M Alexander; Joan K Riley; Emily S Jungheim
Journal:  J Assist Reprod Genet       Date:  2020-08-20       Impact factor: 3.412

3.  Using Surplus Embryos and Research Embryos in Stem Cell Research: Ethical Viewpoints of Buddhist, Hindu and Catholic Leaders in Malaysia on the Permissibility of Research.

Authors:  Mathana Amaris Fiona Sivaraman
Journal:  Sci Eng Ethics       Date:  2017-03-09       Impact factor: 3.525

4.  Patients' attitudes toward the donation of biological materials for the derivation of induced pluripotent stem cells.

Authors:  Ishan Dasgupta; Juli Bollinger; Debra J H Mathews; Neil M Neumann; Abbas Rattani; Jeremy Sugarman
Journal:  Cell Stem Cell       Date:  2014-01-02       Impact factor: 24.633

5.  Of research and reproduction: defining embryo 'Research' in Canada.

Authors:  Alana Cattapan; Dave Snow
Journal:  Monash Bioeth Rev       Date:  2015-12

6.  Patients' views on using human embryonic stem cells to treat Parkinson's disease: an interview study.

Authors:  Jennifer Drevin; Dag Nyholm; Håkan Widner; Trinette Van Vliet; Jennifer Viberg Johansson; Elena Jiltsova; Mats Hansson
Journal:  BMC Med Ethics       Date:  2022-10-19       Impact factor: 2.834

7.  Fertility patients' views about frozen embryo disposition: results of a multi-institutional U.S. survey.

Authors:  Anne Drapkin Lyerly; Karen Steinhauser; Corrine Voils; Emily Namey; Carolyn Alexander; Brandon Bankowski; Robert Cook-Deegan; William C Dodson; Elena Gates; Emily S Jungheim; Peter G McGovern; Evan R Myers; Barbara Osborn; William Schlaff; Jeremy Sugarman; James A Tulsky; David Walmer; Ruth R Faden; Edward Wallach
Journal:  Fertil Steril       Date:  2008-12-05       Impact factor: 7.329

8.  'Not taken in by media hype': how potential donors, recipients and members of the general public perceive stem cell research.

Authors:  V L Peddie; M Porter; C Counsell; L Caie; D Pearson; S Bhattacharya
Journal:  Hum Reprod       Date:  2009-01-24       Impact factor: 6.918

9.  The ethical, legal, and social issues impacted by modern assisted reproductive technologies.

Authors:  Paul R Brezina; Yulian Zhao
Journal:  Obstet Gynecol Int       Date:  2012-01-04

10.  Fresh embryo donation for human embryonic stem cell (hESC) research: the experiences and values of IVF couples asked to be embryo donors.

Authors:  E Haimes; K Taylor
Journal:  Hum Reprod       Date:  2009-06-06       Impact factor: 6.918

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