Literature DB >> 1816418

[Effects of ginseng on hepatocellular carcinoma in rats induced by diethylnitrosamine--a further study].

X Li1, X G Wu.   

Abstract

The curative effects of Panax ginseng on hepatocellular carcinoma (HCC) in rats induced by diethylnitrosamine (DEN) were further studied. The size of cancerous nodes was quantitatively measured by image analysis instrument. The hepatocellular hyperplastic foci were quantitatively analysed with gamma-GT stain under microspectrophotometer. Pathological changes of hepatocytes were observed under light and electron microscope. The results of the investigation indicated that ginseng had significant inhibitory effect on HCC in rats induced by DEN and prolonged the survival time of the rats with HCC. The mechanism of inhibition of the development of HCC by ginseng was also preliminarily approached.

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Year:  1991        PMID: 1816418     DOI: 10.1007/BF02888092

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN: 0257-716X


  6 in total

1.  Induction of phenotypic reverse transformation by ginsenosides in cultured Morris hepatoma cells.

Authors:  S Odashima; Y Nakayabu; N Honjo; H Abe; S Arichi
Journal:  Eur J Cancer       Date:  1979-06       Impact factor: 9.162

2.  Influence of ginseng upon the development of liver cancer induced by diethylnitrosamine in rats.

Authors:  X G Wu; D H Zhu
Journal:  J Tongji Med Univ       Date:  1990

3.  Anticarcinogenic effect of long-term oral administration of red ginseng on newborn mice exposed to various chemical carcinogens.

Authors:  T K Yun; Y S Yun; I W Han
Journal:  Cancer Detect Prev       Date:  1983

4.  Ultrastructural studies of Morris hepatoma cells reversely transformed by ginsenosides.

Authors:  H Abe; S Arichi; T Hayashi; S Odashima
Journal:  Experientia       Date:  1979-12-15

5.  Sequential quantitative studies on hyperplastic nodules in the liver of rats treated with carcinogenic chemicals.

Authors:  M Tatematsu; G Murasaki; K Nakanishi; Y Miyata; Y Shinohara; N Ito
Journal:  Gan       Date:  1979-02

6.  Antihepatotoxic Actions of Ginsenosides from Panax ginseng Roots1.

Authors:  H Hikino; Y Kiso; J Kinouchi; S Sanada; J Shoji
Journal:  Planta Med       Date:  1985-02       Impact factor: 3.352

  6 in total
  1 in total

Review 1.  Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside.

Authors:  Bing Hu; Shuang-Shuang Wang; Qin Du
Journal:  World J Hepatol       Date:  2015-05-28
  1 in total

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