Literature DB >> 18164006

Fixation of long bone segmental defects: a biomechanical study.

Max Talbot1, Rad Zdero, Daniel Garneau, Peter A Cole, Emil H Schemitsch.   

Abstract

OBJECTIVES: Obtaining stable fixation in cases of long bone non-union with segmental bone defects can be challenging. Bone quality is often sub-optimal. Locking plates and structural allografts have both been used clinically in these cases. The objective of this study was to determine the biomechanical characteristics of three constructs that have been employed in this context.
METHODS: A biomechanical study was performed using 3rd Generation Composite Femurs as specimens. A diaphyseal segmental defect was created and fixed with one of three constructs: (1) lateral locking plate (LP); (2) lateral non-locking plate and medial allograft strut (S); (3) lateral non-locking plate and intramedullary fibula allograft (F). The "allografts" were fashioned from 3rd generation composite bones. Axial, torsional and bending stiffness as well as load to failure were determined using a materials testing machine.
RESULTS: Overall, construct S was the stiffest and construct LP was the least stiff. Construct F had intermediate characteristics. Axial load to failure for construct S (6108N) and for construct F (5344N) was significantly greater than for construct LP (2855N).
CONCLUSION: When maximal stiffness is desired, a construct with a structural allograft should be chosen over a locking plate. However, biological and anatomic factors must also be taken into account when using these constructs clinically.

Entities:  

Mesh:

Year:  2007        PMID: 18164006     DOI: 10.1016/j.injury.2007.08.026

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  7 in total

1.  Reconstruction of Large Diaphyseal Defects of the Femur and the Tibia with Autologous Bone.

Authors:  Charles E Dumont; Ulrich G Exner
Journal:  Eur J Trauma Emerg Surg       Date:  2009-01-19       Impact factor: 3.693

2.  Repeated freeze-thaw cycles do not alter the biomechanical properties of fibular allograft bone.

Authors:  Joshua M Shaw; Shawn A Hunter; J Christopher Gayton; Gregory P Boivin; Michael J Prayson
Journal:  Clin Orthop Relat Res       Date:  2011-08-24       Impact factor: 4.176

Review 3.  Pre-Clinical Evaluation of Biological Bone Substitute Materials for Application in Highly Loaded Skeletal Sites.

Authors:  Sónia de Lacerda Schickert; Jeroen J J P van den Beucken; Sander C G Leeuwenburgh; John A Jansen
Journal:  Biomolecules       Date:  2020-06-09

4.  Biomechanical Analysis Using FEA and Experiments of Metal Plate and Bone Strut Repair of a Femur Midshaft Segmental Defect.

Authors:  Jason Coquim; Joseph Clemenzi; Mohsen Salahi; Abdurahman Sherif; Pouria Tavakkoli Avval; Suraj Shah; Emil H Schemitsch; Z Shaghayegh Bagheri; Habiba Bougherara; Radovan Zdero
Journal:  Biomed Res Int       Date:  2018-10-18       Impact factor: 3.411

Review 5.  Complications and Survivorship of Distal Humeral Allograft Reconstruction After Tumor Resection: Literature Review and Case Series.

Authors:  Pramod Kamalapathy; Akash Shah; Kevin Raskin; Joseph H Schwab; Santiago A Lozano-Calderón
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-02-11

6.  Single stage open reduction, intramedullary rod, bone grafting, and plate fixation for managing adolescent midshaft femoral fracture non-union, report of two cases.

Authors:  Omar Refai; Ahmed A Khalifa
Journal:  Trauma Case Rep       Date:  2022-01-31

7.  Spatial Bridge Locking Fixator versus Traditional Locking Plates in Treating AO/OTA 32-A3.2 Fracture: Finite Element Analysis and Biomechanical Evaluation.

Authors:  Jianwei Hu; Ye Peng; Jiantao Li; Ming Li; Ying Xiong; Jiayu Xiao; Licheng Zhang; Peifu Tang
Journal:  Orthop Surg       Date:  2022-06-22       Impact factor: 2.279

  7 in total

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