| Literature DB >> 18163587 |
Rohan A Davis1, Moana M Simpson, Ryan B Nugent, Anthony R Carroll, Vicky M Avery, Topul Rali, Huawei Chen, Barbara Qurallo, Ronald J Quinn.
Abstract
Bioassay-guided fractionation of an organic extract from the leaves of Cupaniopsis macropetala resulted in the isolation of a new alkaloid, galloyl tyramine ( 1), together with the known flavonoid glycoside quercitrin ( 2). The structure of 1 was determined following 1D and 2D NMR, IR, UV, and MS data analysis. Compounds 1 and 2 displayed IC 50 values of 161 and 25 microM, respectively, in a Pim2 enzyme assay.Entities:
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Year: 2007 PMID： 18163587 DOI： 10.1021/np070431w
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050