| Literature DB >> 18160823 |
Michael Rubart1, Loren J Field.
Abstract
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease. Here we review the preclinical studies demonstrating that intracardiac transplantation of skeletal myoblasts, cardiomyocytes and cardiomyogenic stem cells is feasible. In addition, recent clinical studies of skeletal myoblast and adult stem cell transplantation for heart disease are discussed. (c) 2007 S. Karger AG, Basel.Entities:
Mesh:
Year: 2007 PMID: 18160823 PMCID: PMC2605419 DOI: 10.1159/000112846
Source DB: PubMed Journal: Cells Tissues Organs ISSN: 1422-6405 Impact factor: 2.481