Literature DB >> 18158280

Similar prevalence of founder BRCA1 and BRCA2 mutations among Ashkenazi and non-Ashkenazi men with breast cancer: evidence from 261 cases in Israel, 1976-1999.

Gabriel Chodick1, Jeffery P Struewing, Elaine Ron, Joni L Rutter, Jose Iscovich.   

Abstract

To evaluate the potential contribution of mutations in the BRCA1 and BRCA2 genes to male breast cancer (MBC), we expanded a previous study to screen a total of 261 Israeli men diagnosed with breast carcinoma. A total of 21 BRCA2 6174delT and 8 BRCA1 185delAG mutations were found. Similar frequencies of BRCA1 and BRCA2 mutation carriers were found among Ashkenazi (12.8%) and non-Ashkenazi Jews (9.1%). The combined prevalence of BRCA1/BRCA2 founder mutations among Ashkenazi Jewish men is slightly higher than for women, due to a higher frequency of BRCA2 mutations.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 18158280      PMCID： PMC2386175          DOI： 10.1016/j.ejmg.2007.11.001

Source DB:  PubMed          Journal:  Eur J Med Genet        ISSN： 1769-7212            Impact factor:   2.708


  28 in total

Review 1.  Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families.

Authors:  P Tonin; B Weber; K Offit; F Couch; T R Rebbeck; S Neuhausen; A K Godwin; M Daly; J Wagner-Costalos; D Berman; G Grana; E Fox; M F Kane; R D Kolodner; M Krainer; D A Haber; J P Struewing; E Warner; B Rosen; C Lerman; B Peshkin; L Norton; O Serova; W D Foulkes; J E Garber
Journal:  Nat Med       Date:  1996-11       Impact factor: 53.440

2.  Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.

Authors:  L S Friedman; S A Gayther; T Kurosaki; D Gordon; B Noble; G Casey; B A Ponder; H Anton-Culver
Journal:  Am J Hum Genet       Date:  1997-02       Impact factor: 11.025

3.  The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews.

Authors:  J P Struewing; P Hartge; S Wacholder; S M Baker; M Berlin; M McAdams; M M Timmerman; L C Brody; M A Tucker
Journal:  N Engl J Med       Date:  1997-05-15       Impact factor: 91.245

4.  Demographic, clinical and survivorship characteristics of males with primary cancer of the breast.

Authors:  A Z Keller
Journal:  Am J Epidemiol       Date:  1967-03       Impact factor: 4.897

5.  Cancer statistics, 2005.

Authors:  Ahmedin Jemal; Taylor Murray; Elizabeth Ward; Alicia Samuels; Ram C Tiwari; Asma Ghafoor; Eric J Feuer; Michael J Thun
Journal:  CA Cancer J Clin       Date:  2005 Jan-Feb       Impact factor: 508.702

6.  BRCA2 germline mutations in male breast cancer cases and breast cancer families.

Authors:  F J Couch; L M Farid; M L DeShano; S V Tavtigian; K Calzone; L Campeau; Y Peng; B Bogden; Q Chen; S Neuhausen; D Shattuck-Eidens; A K Godwin; M Daly; D M Radford; S Sedlacek; J Rommens; J Simard; J Garber; S Merajver; B L Weber
Journal:  Nat Genet       Date:  1996-05       Impact factor: 38.330

7.  Spectrum of mutations in BRCA1 gene in hereditary forms of breast and ovarian cancer in Russian families.

Authors:  A N Loginova; N I Pospekhova; L N Lyubchenko; A V Budilov; V M Zakhar'ev; R F Gar'kavtseva; E K Ginter; A V Karpukhin
Journal:  Bull Exp Biol Med       Date:  2003-09       Impact factor: 0.804

8.  Risk factors for male breast cancer.

Authors:  K Mabuchi; D S Bross; I I Kessler
Journal:  J Natl Cancer Inst       Date:  1985-02       Impact factor: 13.506

9.  Breast carcinoma in men: a population-based study.

Authors:  Sharon H Giordano; Deborah S Cohen; Aman U Buzdar; George Perkins; Gabriel N Hortobagyi
Journal:  Cancer       Date:  2004-07-01       Impact factor: 6.860

10.  BRCA1 and BRCA2 mutation status and tumor characteristics in male breast cancer: a population-based study in Italy.

Authors:  Laura Ottini; Giovanna Masala; Cristina D'Amico; Biancamaria Mancini; Calogero Saieva; Gitana Aceto; Donella Gestri; Vania Vezzosi; Mario Falchetti; Manola De Marco; Milena Paglierani; Alessandro Cama; Simonetta Bianchi; Renato Mariani-Costantini; Domenico Palli
Journal:  Cancer Res       Date:  2003-01-15       Impact factor: 12.701
View more
  4 in total

1.  Novel germline mutations in BRCA2 gene among breast and breast-ovarian cancer families from Poland.

Authors:  Aneta Balabas; Elzbieta Skasko; Dorota Nowakowska; Anna Niwinska; Pawel Blecharz
Journal:  Fam Cancer       Date:  2010-09       Impact factor: 2.375

2.  The 21-Gene Recurrence Score in Male Breast Cancer.

Authors:  Gulisa Turashvili; Monica Gonzalez-Loperena; Edi Brogi; Maura Dickler; Larry Norton; Monica Morrow; Hannah Y Wen
Journal:  Ann Surg Oncol       Date:  2018-03-08       Impact factor: 5.344

3.  Multidisciplinary meeting on male breast cancer: summary and research recommendations.

Authors:  Larissa A Korde; Jo Anne Zujewski; Leah Kamin; Sharon Giordano; Susan Domchek; William F Anderson; John M S Bartlett; Karen Gelmon; Zeina Nahleh; Jonas Bergh; Bruno Cutuli; Giancarlo Pruneri; Worta McCaskill-Stevens; Julie Gralow; Gabriel Hortobagyi; Fatima Cardoso
Journal:  J Clin Oncol       Date:  2010-03-22       Impact factor: 44.544

4.  Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas.

Authors:  Pedro Pinto; Ana Peixoto; Catarina Santos; Patrícia Rocha; Carla Pinto; Manuela Pinheiro; Luís Leça; Ana Teresa Martins; Verónica Ferreira; Carla Bartosch; Manuel R Teixeira
Journal:  PLoS One       Date:  2016-08-17       Impact factor: 3.240
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.